Hormone replacement therapy (HRT) with conjugated equinestrogens (CEE) plus medroxyprogeserone acetate (MPA) or CEE alone does not increase the risk of cardiovascular (CV) mortality among postmenopausal women, according to an expert who reviewed 18-year follow-up data of the Women’s Health Initiative (WHI) randomized trials at the Endocrinology, Diabetes Metabolism Hong Kong (EDMHK) 2nd Annual Meeting.
Denosumab is superior to risedronate in increasing spine and hip bone mineral density (BMD) through month 24 and may be a new treatment option for patients with glucocorticoid-induced osteoporosis (GIOP), according to results of a multicentre, randomized, phase III trial.
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The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Extremes of sleep duration (≤5 or ≥10 hours/day), which is a known mortality risk factor in the general population, may increase absolute mortality in adults with type 2 diabetes (T2D), a prospective study has shown.
Insulin icodec, an in-development basal insulin analogue administered once weekly, was as effective as once-daily insulin glargine in patients with type 2 diabetes (T2D) insufficiently controlled with metformin with or without a DPP-4* inhibitor, according to a phase II trial presented at EASD 2020.