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Top Medical News
Patient-reported outcomes in several physical and mental health domains are poorer among users of traditional Chinese medicine (TCM), according to a study of Chinese American rheumatology patients. However, TCM may be used as an alternative for unmet therapeutic needs.
Women who had experienced physical and emotional abuse during childhood appear to have a significantly higher risk of systemic lupus erythematosus (SLE) than those who had not, a recent study reveals. Exposure to childhood adversity may be a risk factor for SLE development.
A personalized approach in the dosing of subcutaneous tocilizumab (TCZ) injections according to body weight appears to be effective in improving outcomes of clinical disease activity in patients with rheumatoid arthritis (RA), suggests a study.
Denosumab appears to have a neutral effect on the risk of composite and specific cardiovascular outcomes among patients with primary osteoporosis, whereas romosozumab may contribute to an increased risk of four-point major adverse cardiovascular event, according to the results of a meta-analysis.
The efficacy of biologic drugs for psoriatic arthritis appears to decrease in the presence of comorbid fibromyalgia, especially among female patients with obesity, according to a study.
New drug applications approved by US FDA as of 16 - 30 November 2019 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Women with late age at menarche are at much lower risk of developing systemic sclerosis (SSc), a study suggests. Furthermore, abortion does not contribute to a risk increase.
Special Reports
With the objective of establishing a Malaysian consensus on the use of topical NSAIDs in the management of musculoskeletal pain, this meeting brought together experts from various backgrounds, ie, rheumatology, pharmacy, orthopaedics and general medicine. At the meeting, Dr Mary Suma Cardosa delivered a talk on the pathophysiology and effective management of pain, while the lecture by Dr Yeap Swan Sim focused on the management of musculoskeletal and soft-tissue pain. This article presents excerpts from the expert meeting and features the consensus statements agreed during the meeting.
At the International Osteoporosis Foundation Regionals – 6th Asia-Pacific Osteoporosis Meeting in Singapore, Professor Olivier Bruyère shared about the algorithm for the management of knee OA by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). MIMS Doctor also spoke to Professor Jean-Yves Reginster, president of ESCEO about this algorithm and the role of SYSADOAs in the control of pain and prevention of disease progression.
Conference Reports
Privacy and transparency are among the core points to consider when utilizing big data in rheumatic and musculoskeletal disorders (RMDs), according to the first EULAR-endorsed recommendations for use of big datasets in research.
A combination of tocilizumab and methotrexate reduced disease activity at 2 years compared with methotrexate plus prednisone in patients with early rheumatoid arthritis (RA), an effect not demonstrated with tocilizumab monotherapy.
Patients with painful hand osteoarthritis can finally get relief from pain with low-dose prednisolone, suggests a study presented at EULAR 2019.
Occupational exposure to inorganic dust, particularly asbestos, silica, and coal, was associated with an increased risk of developing gout, according to a study presented at EULAR 2019.
Being overweight may have an impact on disease severity in psoriatic arthritis, according to a study presented at EULAR 2019.
The selective Janus kinase 1 inhibitor upadacitinib demonstrated sustained efficacy and safety beyond 12 weeks in patients with moderate-to-severe rheumatoid arthritis (RA) who had inadequate response or were refractory to disease-modifying antirheumatic drugs (DMARDs), according to the interim results of the ongoing extension phases of SELECT-NEXT* and SELECT-BEYOND** presented at EULAR 2019.
Both inflammatory bowel disease (IBD) and type 1 diabetes (T1D) are highly prevalent among patients who eventually develop rheumatoid arthritis (RA), indicating that these two conditions are potential risk factors for RA, according to a study presented at EULAR 2019.
