Top Medical News
2 days ago
Women are more likely to have a lower rate of response to treatment and of disease remission in axial spondyloarthritis (axSpA) treated with antitumour necrosis factor (anti-TNF)-α medications, according to a recent study.
3 days ago
The use of opioid analgesics among patients with ankylosing spondylitis (AS) appears to be associated with subjective measures (depression, Bath Ankylosing Spondylitis Disease Activity Index [BASDAI], Bath Ankylosing Spondylitis Functional Index [BASFI]) than objective measures (C-reactive protein [CRP], erythrocyte sedimentation rate [ESR]), according to a study.
3 days ago
Women with rheumatoid arthritis (RA) appear to have better functional status prior to menopause, with a recent study reporting that menopause is associated with a worsening progression of functional decline in RA.
Tristan Manalac, 4 days ago
Low-dose oral colchicine appears to be effective at controlling knee osteoarthritis (KOA) progression and severity by reducing inflammation and high bone turnover markers, according to a recent Singapore study. On the other hand, it does not improve KOA symptoms in the short term.
Pearl Toh, 4 days ago
Menopause was associated with worsening of physical function in women with rheumatoid arthritis (RA), suggests a study.
5 days ago
Short-term treatment with methotrexate at >0.5 defined daily dose (8.75 mg/week) may help reduce the risk of ischaemic stroke in rheumatoid arthritis (RA) patients, while hydroxychloroquine and sulfasalazine have neutral effects, a retrospective study has found.
10 Feb 2018
Elastic band resistance training (ERT) is associated with improvements in muscle mass, physical function and muscle quality in elderly females, a recent study has shown.
Special Reports
28 Nov 2017
At the 47th Annual Scientific Meeting/Annual General Meeting of the Malaysian Orthopaedic Association, Dr Algis Jovaisas discussed important clinical considerations when it comes to choosing between nonselective nonsteroidal anti-inflammatory drugs (nsNSAIDs) and selective COX-2 inhibitors (coxibs) for the management of acute pain.
01 Jul 2017
At the recent launch of Nurofen® Express by Reckitt Benckiser Malaysia, Ms Joyce McSwan spoke on the importance of managing tension-type headache (TTH), highlighting the roles of drug and non-drug approaches in improving treatment outcomes.
03 Apr 2017
At the International Osteoporosis Foundation Regionals – 6th Asia-Pacific Osteoporosis Meeting in Singapore, Professor Olivier Bruyère shared about the algorithm for the management of knee OA by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). MIMS Doctor also spoke to Professor Jean-Yves Reginster, president of ESCEO about this algorithm and the role of SYSADOAs in the control of pain and prevention of disease progression.
07 Mar 2017
At the 17th Malaysian Society of Rheumatology/Singapore Society of Rheumatology Workshop, Associate Professor Susanna Proudman, a senior consultant in rheumatology from Australia, shared with the audience on the diagnosis and management of pulmonary arterial hypertension (PAH), with a focus on systemic sclerosis (SSc)-related PAH.
18 Aug 2016
During the combined meeting of the 46th Malaysian Orthopaedic Association Annual General Meeting/Annual Scientific Meeting and the 10th ASEAN Arthroplasty Association Meeting, Dr Joseph Pergolizzi spoke on the importance of chronic pain control and appropriate strategies to achieve this. Highlights of his presentation are summarized below.
13 May 2015
Recently, MIMS Doctor sat down with Associate Professor Dr Sabarul Afian Mokhtar to get his perspectives on the use of monoclonal antibody for the treatment of postmenopausal osteoporosis (PO) and also important learning from the International Osteoporosis Foundation (IOF) Regionals 5th Asia-Pacific Osteoporosis Meeting. Highlights from the interview are presented here.
Naomi Adam, 01 Feb 2014

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, the underlying cause of which is not fully known. Recently, biologic disease-modifying anti-rheumatic drugs (DMARDs) have started to be considered for the treatment of SLE due to their improved tolerability profiles compared with conventional therapies. This report profiles belimumab, a novel biologic DMARD, which has been approved for use in the treatment of certain patients with SLE.

Conference Reports
Jairia Dela Cruz, 22 Dec 2017
The monoclonal antibody denosumab demonstrates potent antiresorptive effect in the treatment of osteoporosis, conferring benefit for fracture risk and averting bone loss in select oncological situations. The drug must be used without interruption to prevent a rebound effect, according to Dr Tai-Pang Ip, a consultant endocrinologist from Hong Kong who spoke at AFOS 2017 held in Kuala Lumpur, Malaysia.
Elvira Manzano, 17 Oct 2017
Bisphosphonates have proven antifracture efficacy and remain to be the cornerstone of osteoporosis treatment. However, a drug holiday is of particular importance with bisphosphonates due to some signals with long-term use of the drug, including rare incidence of atypical femoral fracture (AFF) and osteonecrosis of the jaw (ONJ), says a leading endocrinologist at AFOS 2017.
Audrey Abella, 17 Oct 2017
The use of functional imaging modalities such as octreotide scintigraphy and 68Ga DOTATATE PET/CT* enhances localization of tumour-induced osteomalacia (TIO), a rare syndrome characterized by bone pain, muscle weakness, and skeletal deformities due to overproduction of the hormone fibroblast growth factor 23 (FGF23), according to data presented at AFOS 2017.
17 Oct 2017
Slideshow: Highlights from the Asian Federation of Osteoporosis Societies (AFOS 2017) 5th Annual Scientific Meeting
Elvira Manzano, 16 Oct 2017
Osteoporosis is an age-related complex disease with a strong genetic component. However, the genes responsible for the disease remain poorly defined, says an expert at AFOS 2017.
Stephen Padilla, 16 Oct 2017
Elderly patients with osteoporotic vertebral fractures (OVF) should refrain from undergoing highly invasive surgery, but those with no posterior wall mobility or paralysis may benefit from balloon kyphoplasty (BKP) for OVF with posterior vertebral wall damage, according to a study presented at the 5th Scientific Meeting Asian Federation of Osteoporosis Societies (AFOS) 2017 in Kuala Lumpur, Malaysia.
13 Oct 2017
Dr Joon Kiong Lee discusses pharmacotherapy for osteoporosis and the role of FLS in fracture prevention
CME Modules
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