Top Medical News
Jairia Dela Cruz, Yesterday
Biweekly treatment with pegloticase yields favourable effects on systolic and diastolic blood pressure as well as mean arterial pressure in gout patients who maintain a persistently low serum urate, and these effects are independent of changes in renal function, according to a posthoc analysis of two trials.
In a US-based registry, only a few patients with psoriatic arthritis (PsA) on tumour necrosis factor inhibitor (TNFi) have achieved remission using the Clinical Disease Activity Index (CDAI) criteria, according to a new study, noting that female sex, obesity, comorbidities and education are associated with achieving remission.
Jairia Dela Cruz, 5 days ago
Tofacitinib yields clinical and radiographic improvements in rheumatoid arthritis (RA) patients with inadequate response to methotrexate, and such improvements are sustained for up to 24 months without new safety signals, according to the results of the phase III ORAL* Scan trial.
5 days ago
Recent continuous use of methotrexate (MTX) is associated with a 20-percent decrease in cardiovascular events (CVE) in patients with early-onset rheumatoid arthritis (RA), a recent study has shown. In addition, greater MTX use in the first year of cohort entry appears to lower the risk of CVE.
13 May 2019
Use of atorvastatin in patients with rheumatoid arthritis is safe and leads to substantial reductions in low-density lipoprotein cholesterol, which translates to a 40-percent decrease in the risk of cardiovascular events, according to data from the TRACE RA trial.
10 May 2019
Increases in levels of high-density lipoprotein (HDL-C) but not low-density lipoprotein or total cholesterol after 24 weeks of tofacitinib treatment translate to a lower risk of future major adverse cardiovascular events, according to a study.
02 May 2019
Initiation of biologic therapy is less frequent among patients with rheumatoid arthritis (RA) who are older, nonwhite and have more comorbidities, according to a recent study. Biologics may be avoided in older and sicker patients due to safety concerns, but glucocorticoid use is similar regardless of age and more common in patients with comorbidities, with implications for patient outcomes.
01 Jul 2018
With the objective of establishing a Malaysian consensus on the use of topical NSAIDs in the management of musculoskeletal pain, this meeting brought together experts from various backgrounds, ie, rheumatology, pharmacy, orthopaedics and general medicine. At the meeting, Dr Mary Suma Cardosa delivered a talk on the pathophysiology and effective management of pain, while the lecture by Dr Yeap Swan Sim focused on the management of musculoskeletal and soft-tissue pain. This article presents excerpts from the expert meeting and features the consensus statements agreed during the meeting.
28 Nov 2017
At the 47th Annual Scientific Meeting/Annual General Meeting of the Malaysian Orthopaedic Association, Dr Algis Jovaisas discussed important clinical considerations when it comes to choosing between nonselective nonsteroidal anti-inflammatory drugs (nsNSAIDs) and selective COX-2 inhibitors (coxibs) for the management of acute pain.
01 Jul 2017
At the recent launch of Nurofen® Express by Reckitt Benckiser Malaysia, Ms Joyce McSwan spoke on the importance of managing tension-type headache (TTH), highlighting the roles of drug and non-drug approaches in improving treatment outcomes.
The ESCEO algorithm for the management of knee osteoarthritis (OA) and the role of symptomatic slow-acting drugs for OA (SYSADOAs)
03 Apr 2017
At the International Osteoporosis Foundation Regionals – 6th Asia-Pacific Osteoporosis Meeting in Singapore, Professor Olivier Bruyère shared about the algorithm for the management of knee OA by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO). MIMS Doctor also spoke to Professor Jean-Yves Reginster, president of ESCEO about this algorithm and the role of SYSADOAs in the control of pain and prevention of disease progression.
Audrey Abella, 25 Jul 2018
The human anti-interleukin (IL)-1β monoclonal antibody canakinumab continued to show optimal control of disease activity (ie, one or no new flare, no uptitration) in patients with colchicine-resistant familial Mediterranean fever (crFMF), TNF* receptor-associated periodic syndrome (TRAPS), and hyper IgD** syndrome (HIDS)/mevalonate kinase deficiency (MKD) after 112 weeks, according to results from the fourth phase of the CLUSTER*** trial presented at EULAR 2018.
Elvira Manzano, 29 Jun 2018
Treatment with the immunomodulatory agent canakinumab reduces the risk of gout flares by more than half in patients with atherosclerosis, according to the post hoc analysis of the CANTOS* trial.
Pearl Toh, 28 Jun 2018
More than half of the increase in cardiovascular disease (CVD) risk associated with osteoarthritis can be attributed to the use of nonsteroidal anti-inflammatory drugs (NSAIDs), suggests a study presented at the EULAR 2018 Congress.
Elaine Soliven, 28 Jun 2018
Pregnant women with rheumatoid arthritis (RA) are more likely to have premature delivery or baby of low birth weight compared with women without RA, according to a study presented at EULAR 2018.
Roshini Claire Anthony, 27 Jun 2018
Patients with rheumatoid arthritis have a similar incidence of cancer regardless of whether they are treated with tocilizumab or tumour necrosis factor (TNF) inhibitors, according to a study presented at EULAR 2018.
Pearl Toh, 25 Jun 2018
Patients with ankylosing spondylitis (AS) derived a greater benefit from tumour necrosis factor (TNF) inhibitors in terms of less radiographic progression when they also took non-steroidal anti-inflammatory drugs (NSAIDs), suggests a cohort study presented at the EULAR 2018 Congress.
Stephen Padilla, 25 Jun 2018
Although majority of Takayasu arteritis (TA) pregnancies are uneventful and have favourable foetal and maternal outcomes, pregnant TA patients with active disease are at increased risk of developing maternal complications, particularly cardiovascular events, according to a study presented at the European League Against Rheumatism (EULAR) Congress 2018.