Use of the oral phosphodiesterase-5 inhibitor udenafil in the treatment of patients with pulmonary arterial hypertension is safe and leads to a significant increase in exercise capacity, according to the results of a phase IIB trial.
Nocturnal oxygen desaturation (NOD) is associated with poorer overall (OS) and progression-free survival (PFS) and may contribute towards the development of pulmonary vascular disease in patients with interstitial lung disease (ILD), according to a study.
Exposure to secondhand smoke during childhood is associated with an increased risk of atrial fibrillation (AF) later in life, thus presenting childhood secondhand smoke exposure as a modifiable risk factor for AF, the Framingham Heart Study finds.
Radiation heart dosimetric parameters appear to exert neutral effect on overall survival (OS) in nonsmall cell lung cancer patients undergoing postoperative thoracic radiotherapy (PORT), according to a recent Singapore study.
The use of songs as mental metronomes for cardiopulmonary resuscitation (CPR) is accepted by contemporary guidelines, and the National Day song ‘Count on me Singapore’ (COMS) is not an exception, with a recent study finding it noninferior to standard ‘one-and-two-and-three’ counting (standard CPR) in terms of participants delivering a guideline-compliant rate of chest compression.
Influenza burden in Singapore has been on the rise since 2010, with young children (aged ≤4 years) and the elderly (aged ≥65 years) being most susceptible to influenza‐associated hospitalization for pneumonia and influenza (P&I), a local study has shown.
Oral amoxicillin–clavulanate effectively promotes resolution of nonsevere acute exacerbations in children with non-cystic
fibrosis (CF) bronchiectasis, thus confirming the role of amoxicillin–clavulanate as first-line treatment for bronchiectasis, according to results from the three-arm BEST-1 study.
A management strategy of C-reactive protein (CRP) point-of-care testing for exacerbations of chronic obstructive pulmonary disease (COPD) minimizes physician’s prescription and patient’s use of antibiotics without compromising disease-specific quality of life, as shown in the results of PACE trial.
Treatment with corticosteroids (CS) plus intravenous cyclophosphamide (IVCY) for a first episode of idiopathic acute exacerbation (AE) does not significantly improve short-term survival as compared with CS monotherapy in patients with idiopathic pulmonary fibrosis (IPF), a study has found.
Dr Ong Kian Chung, a respiratory specialist at the KC Ong Chest & Medical Clinic, Mount Elizabeth Medical Centre, Singapore spoke on the evils of tobacco use and how clinicians can help in smoking cessation.
The prevalence of allergic diseases in the Asia-Pacific region is expected to rise over the next 20 years, driven by rapid economic development and urbanization. Allergic diseases have high socioeconomic impact by impairing productivity and quality of life, and the impact may be greater in Asia-Pacific than in Europe due to the presence and predominance of perennial allergens.