The use of single-inhaler triple therapy yields meaningful improvements across a range of chronic obstructive pulmonary disease (COPD) endpoints over time compared with dual therapies, according to data from the IMPACT* trial presented at the 2019 European Respiratory Society (ERS) International Congress.
Adding a LAMA* to the double combination therapy of ICS** plus LABA*** in a single inhaler improves lung function and reduces exacerbations in patients whose asthma is inadequately controlled with the combination treatment, according to the TRIMARAN and TRIGGER# studies presented at ERS 2019.
Maintenance therapy with the common macrolide antibiotic azithromycin halves the rate of respiratory events in patients with primary ciliary dyskinesia (PCD) – otherwise known as immotile-cilia syndrome – in the first multicentre randomized controlled clinical trial of azithromycin in PCD.
Babies born to mothers exposed to high levels of bisphenol A during pregnancy are at a greater risk of wheezing and poor lung function, according to a new study presented at the recently concluded International Congress of the European Respiratory Society (ERS 2019).
Transbronchial lung cryobiopsy performs well in diagnosing interstitial lung disease, showing an accuracy similar to that of surgical lung biopsy, according to the results of the COLDICE study presented at the European Respiratory Society (ERS) International Congress 2019.
Dupilumab significantly improves all disease components of severe, uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) — a primarily type 2 inflammatory condition — compared with placebo when both are added to standard of care. Furthermore, the treatment benefit extends to even patients with comorbid nonsteroidal anti-inflammatory drug-exacerbated respiratory disease (NSAID-ERD), according to a pooled analysis of the LIBERTY NP SINUS-24 and -52* trials presented at ERS 2019.
Final overall survival (OS) results from the double-blind phase III FLAURA study reinforce osimertinib as the standard frontline treatment for epidermal growth factor receptor-mutated (EGFRm) non–small cell lung cancer (NSCLC), say leading oncologists at ESMO 2019.
The tyrosine kinase inhibitor nintedanib significantly delayed progression of a wide range of fibrosing interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis (IPF) compared with placebo, according to the INBUILD* study presented at ERS 2019.
Patients presenting with upper respiratory infections (URIs) are commonly treated with intramuscular corticosteroids (IMCSs) injection, although the practice is not recommended by guidelines — indicating that IMCSs are overused in this setting, according to a study presented at The American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNSF) 2019 Annual Meeting held recently in New Orleans, Louisiana, US.
Healthcare personnel (HCP) who use medical masks when in contact with patients with respiratory illness are no more likely to acquire influenza or other viral respiratory illnesses than HCPs who use N95 respirators, according to the ResPECT* study.
Dr Ong Kian Chung, a respiratory specialist at the KC Ong Chest & Medical Clinic, Mount Elizabeth Medical Centre, Singapore spoke on the evils of tobacco use and how clinicians can help in smoking cessation.