Comprehensive recommendations on coronavirus disease 2019 (COVID-19) for cancer patients have become available following review of guidelines from 63 national/international oncology societies. [Lancet Oncol 2020, doi: 10.1016/S1470-2045(20)30278-3]
Patients with chronic obstructive pulmonary disease (COPD) are at significantly increased risk for all-cause mortality compared to those without COPD, with lung cancer and chronic lower airway disease being the leading causes of death in at-risk patients, particularly those aged <60 years, reveals a study.
There appears to be a low overall incidence of respiratory adverse events during intramuscular (IM) ketamine sedation in paediatric patients in an emergency department (ED) in Singapore, reports a study. Increased incidence is significantly predicted by age <3 years and a higher initial dose of IM ketamine (4 mg/kg), while a lower risk is associated with manipulation and reduction procedures.
Patients with coronavirus disease 2019 (COVID-19) have significant gut dysbiosis that persists even after viral clearance and resolution of respiratory symptoms, according to a metagenomic study by the Chinese University of Hong Kong (CUHK). These findings have led to the development of a probiotic supplement expected to be available in a few months.
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
Pembrolizumab in combination with chemotherapy significantly improves progression-free survival (PFS) vs chemotherapy alone in patients with previously untreated, locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC), results of the KEYNOTE-355 study have shown.