The tetracycline omadacycline is not inferior to moxifloxacin when used as empirical monotherapy for hospitalized adults with community-acquired bacterial pneumonia, according to the results of a phase III study.
Epicutaneous immunotherapy for peanut allergy delivered through a skin patch yields significantly greater response in terms of desensitization to peanut protein than placebo among children with peanut allergy, but misses a component of the primary endpoint to be considered “positive”, according to the PEPITES* study.
Patients with extensive stage small cell lung cancer (ES-SCLC) without brain metastasis who underwent prophylactic cranial irradiation (PCI) after achieving stable disease or better on first-line chemotherapy had improved overall survival (OS) compared with those who did not undergo PCI, according to a retrospective study from Singapore.
Using inhaled ciprofloxacin (ARD-3150) to treat non-cystic fibrosis bronchiectasis associated with chronic Pseudomonas (P.) aeruginosa lung infection yields inconsistent results in the ORBIT trials, necessitating that further studies be done to validate the efficacy of ARD-3150.
Adults who have obstructive sleep apnoea (OSA) with excessively sleepy subtype are at a higher risk of cardiovascular diseases (CVD) compared with those without excessive daytime sleepiness, a study shows.
Results of a Singapore study have shown the effectiveness of a structure pharmacist-led cessation counselling in reducing smoking rates. Smoking cessation can thus be made a part of the holistic management of dermatological conditions.
Dr Ong Kian Chung, a respiratory specialist at the KC Ong Chest & Medical Clinic, Mount Elizabeth Medical Centre, Singapore spoke on the evils of tobacco use and how clinicians can help in smoking cessation.
Vitamin D supplements can help reduce the rate of moderate-to-severe COPD* exacerbations in patients with inadequate vitamin D levels (<25 nmol/L) at baseline, but not in those with higher levels, according to a meta-analysis of randomized controlled trials (RCTs).
Getting vaccinated against influenza can improve survival of patients with heart failure (HF), with earlier and more frequent vaccination being associated with a greater protection against deaths from cardiovascular (CV) events or any cause, a large Danish nationwide cohort study shows.