New therapies that specifically target inflammatory pathways or aberrant physiology in severe asthma offer substantial opportunities for effective treatment. Some of these therapies are available under specialist referral, and others are available in the context of clinical trials.
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The immediate reduction of cigarette nicotine content results in greater improvements in levels of smoke exposure biomarkers than gradual reduction, though withdrawal symptoms are stronger, according to a recent study.
Continuous positive airway pressure (CPAP), a noninvasive ventilation, may help improve respiratory rate and reduce mortality in children with respiratory distress, particularly in those younger than 1 year, a recent study showed. CPAP intervention was initiated by nurses with minimal physician supervision in the study, supporting the use of noninvasive ventilation in low-resource settings where laboratory diagnostic tests are not readily available.