Use of corticosteroid is not associated with improved outcomes in idiopathic pulmonary fibrosis (IPF) patients admitted to the hospital with acute exacerbation (AE), reveals a recent study. In addition, corticosteroids may even contribute to reduced overall survival following exacerbation.
Children with controlled asthma and severe asthma appear to have slightly better school performances than their healthy counterparts, a recent study suggests. However, those with uncontrolled conditions perform worse.
MicroRNA-4508 shows promise as a diagnostic marker for silica-related pulmonary fibrosis (SPF), while its functional variant rs6576457 has been shown to influence susceptibility to SPF, according to a study.
In infants born extremely premature, immunization with palivizumab does not confer apparent protective effects on respiratory symptoms and pulmonary function at adolescence, as reported in a recent study. Nevertheless, immunized survivors of extreme prematurity show good clinical and physiological outcomes.
Treatment with the serotonin-norepinephrine reuptake inhibitor venlafaxine in patients with obstructive sleep apnoea (OSA) does not yield significant improvements in the apnoea–hypopnea index and even appears to worsen sleep architecture, as shown in a study.
Use of noninvasive ventilation (NIV), similar to invasive mechanical ventilation (IMV), appears to lessen mortality but may increase the risk for transmission of the novel coronavirus disease (COVID-19) in healthcare workers, suggest the results of a study.
At present, there are no definitive treatments for COVID-19. More than 300 clinical trials are ongoing in the search for a cure. Some of the treatments being tested were previously used, with varying levels of efficacy, in the treatment of severe acute respiratory syndrome (SARS) or Middle East respiratory syndrome (MERS).
The gap in overall life expectancy between people with HIV (PWH) and those without HIV has narrowed over time, particularly among optimally treated PWH. However, PWH still have fewer comorbidity-free years than those without HIV, according to a study presented at CROI 2020.