There appears to be a “highly expressed” osteopontin in the lungs of patients with severe pulmonary arterial hypertension (PAH), and this level of expression is significantly associated with disease severity, according to a study, suggesting a major role for osteopontin in the vascular remodelling process of PAH.
Impaired lung function modestly improves lung cancer prediction in nonsmokers, a recent study has found. In turn, asthma, obesity, air pollution and low birthweight are all associated with worse lung function.
A recent study has suggested the use of spectrum analysis of endobronchial ultrasound (EBUS) radiofrequency in predicting malignant or benign peripheral pulmonary lesions (PPL) noninvasively in patients with lung cancer.
Treatment with the neurokinin-1 receptor antagonist orvepitant appears to be safe in patients with chronic refractory cough, yielding sustained improvements in cough frequency and severity, according to the results of the phase II VOLCANO-1 trial.
Patients with chronic obstructive pulmonary disease (COPD) who feel lonely and socially isolated are more likely to visit the emergency department (ED), with their perceived health status being poor, a study has shown.
The transient use of opioids is strongly associated with acute respiratory exacerbation of chronic obstructive pulmonary disease (COPD), and this risk increases with the average daily opioid dose, a study has found.
The use of e-cigarettes changes the innate defence protein profiles in airway secretions, a new study has shown. These changes may lead to questions about e-cigarettes as the supposed healthier alternative to smoking.
Investigators from The University of Hong Kong (HKU) recently identified a mutation in H7N9 virus which causes the virus to possess a higher ability to infect humans while maintaining its ability to circulate effectively in poultry.