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CGP detects EGFR mutations in NSCLC missed by standard-of-care testing

Roshini Claire Anthony, 15 hours ago

Hybrid capture-based comprehensive genomic profiling (CGP) may have the capability to detect epidermal growth factor receptor (EGFR) point mutations in non-small cell lung cancer (NSCLC) that were missed by standard-of-care molecular EGFR testing, a recent study found.

Indacaterol/glycopyrronium more cost-effective for moderate-to-severe COPD

Tristan Manalac, 10 Apr 2018

In patients with moderate-to-severe chronic obstructive pulmonary disease (COPD), the drug combination of indacaterol/glycopyrronium (IND/GLY) is more cost-effective than the inhaled combination of salmeterol/fluticasone (SFC), a recent Singapore study has found.

RSV prevention in infancy has minimal impact on asthma in early childhood

Roshini Claire Anthony, 09 Apr 2018

Prophylaxis for respiratory syncytial virus (RSV) infection in healthy preterm infants reduced their risk of parent-reported (but not physician-diagnosed) asthma at age 6 years, with no apparent effect on lung function, according to follow-up results of the MAKI* study.

Parental smoking during pregnancy, male puberty linked to increased risk of asthma in offspring

07 Apr 2018

Tobacco use by fathers during early adolescence and by mothers during pregnancy may contribute to an increased risk of asthma in offspring, according to data from the Ageing Lungs in European Cohorts (ALEC) Study.

Certain asthma medication tied to infertility in women

Pearl Toh, 07 Apr 2018

Managing asthma with short-acting β-agonists (SABAs) was associated with reduced fertility in women, while the use of inhaled corticosteroids (ICS) with or without long-acting β-agonists (LABAs) was not, according to the SCOPE* study.

Intermittent, high-dose glucocorticoids do not raise risk of fractures in COPD patients

05 Apr 2018

There appears to be no association between the use of intermittent, high-dose glucocorticoids (GCs) and a higher risk of fractures in patients with chronic obstructive pulmonary disease (COPD), a recent study has shown.

Contemporary management of paediatric respiratory diseases: A novel combo of secretolytic and bronchospasmolytic actions

22 Jan 2018

During the recent 2017 Engelhard-Delfi Conference, organized by Delfi Marketing Sdn Bhd, three renowned speakers shared their insights into paediatric respiratory medicine.

Advancing the treatment paradigm of idiopathic pulmonary fibrosis (IPF)

22 Jan 2018

Literature suggests that IPF is either the first or second most common interstitial lung disease (ILD) in pulmonology practice, with prevalence ranging from 17–86%. At the recent 3rd Respiratory Forum organized by Boehringer Ingelheim, Dr Felix Chua shared his insights into the importance of advancing the treatment paradigm of IPF, and the role of nintedanib (OFEV^®) in its management.

The importance of inhaler devices in the management of asthma and chronic obstructive pulmonary disease

05 Jan 2018

At a recent dinner symposium at Shangri-La Kuala Lumpur, Dr Omar Usmani discussed the importance of inhaler devices in the management of asthma and chronic obstructive pulmonary disease (COPD).

Antihistamine therapy for allergic rhinitis and urticaria: An Asia-Pacific perspective

27 Dec 2017

The prevalence of allergic diseases in the Asia-Pacific region is expected to rise over the next 20 years, driven by rapid economic development and urbanization. Allergic diseases have high socioeconomic impact by impairing productivity and quality of life, and the impact may be greater in Asia-Pacific than in Europe due to the presence and predominance of perennial allergens.

Relvar Ellipta: Is once-daily dosing the practical choice for asthma maintenance?

18 Dec 2017

At a GlaxoSmithKline-sponsored symposium during the Malaysian Thoracic Society Annual Congress 2017, Dr Celeste Mae Lardizabal-Campomanes presented on three key strategies of optimizing asthma treatment.

Evolution of influenza vaccines – broader protection for patients with chronic respiratory diseases and lung cancer

04 Oct 2017

At the Malaysian Thoracic Society Annual Scientific Congress 2017 held recently in Kuala Lumpur, Associate Professor Pang spoke on the importance of influenza vaccination in patients with chronic respiratory diseases and lung cancer, highlighting the benefit of quadrivalent influenza vaccines (QIVs) in providing a wider spectrum of protection against influenza types A and B.

Food remains the most common anaphylactic trigger

Audrey Abella, 29 Mar 2018

Food continues to be the most common trigger for anaphylaxis, a rapid-onset and potentially fatal hypersensitivity reaction, according to evidence presented at the AAAAI/WAO* Joint Congress 2018 held in Orlando, Florida, US.

No reduction in asthma exacerbation with temporary glucocorticoid dose increase

Roshini Claire Anthony, 27 Mar 2018

A temporary increased dose of inhaled glucocorticoids did not reduce the rate of exacerbations in children with mild-to-moderate asthma, according to a study presented at the 2018 AAAAI/WAO congress held in Orlando, Florida, US.

Eosinophilic oesophagitis a late manifestation of atopic march in children

Roshini Claire Anthony, 23 Mar 2018

Eosinophilic oesophagitis appears to be a late manifestation of the atopic march, according to a study presented at the recent 2018 AAAAI/WAO* congress held in Orlando, Florida, US.

Indacaterol/glycopyrronium use tied to lower exacerbation risk in patients with COPD

Elaine Soliven, 09 Dec 2017

The use of indacaterol/glycopyrronium (IND/GLY) may reduce exacerbation risk in patients with chronic obstructive pulmonary disease (COPD), according to the DACCORD* study presented at APSR 2017.

Controversies in paediatric empyema management: Fibrinolytics or surgery?

Pearl Toh, 06 Dec 2017

Chest drain with fibrinolytics is as good as video-assisted thoracoscopic surgery (VATS) in the management of childhood empyema, with fibrinolytics being a cheaper option than VATS, according to a presentation at the APSR 2017 Congress.

GORD diagnosis, treatment has little bearing on IPF survival

Roshini Claire Anthony, 05 Dec 2017

Being diagnosed or treated for gastro-oesophageal reflux disease (GORD) has little impact on the survival outcomes of patients with idiopathic pulmonary fibrosis (IPF), according to a study presented as a poster at APSR 2017.

Direct switching to a dual bronchodilator offers benefits in COPD

Elvira Manzano, 05 Dec 2017

Switching from salmeterol/fluticasone (SFC) to indacaterol/glycopyrronium (IND/GLY) improved lung function in patients with symptomatic, moderate-to-severe, chronic obstructive pulmonary disease (COPD), with a tolerability profile similar to SFC, the multicentre, double-blind, double-dummy, parallel-group phase IV FLASH study has shown.

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