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Is asthma a risk factor for AF?

Pearl Toh, 2 days ago

Individuals with asthma had an increased risk of developing atrial fibrillation (AF) than asthma-free individuals, with those who had active or uncontrolled asthma having the highest risk, according to the HUNT* study.

Original New Drug Application Approvals by US FDA (1 - 15 July 2018)

6 days ago

New drug applications approved by US FDA as of 1 - 15 July 2018 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Initial CPAP uptake predictive of 1-year adherence in patients with OSA

Pearl Toh, 12 Jul 2018

Over three-quarter of Singaporean patients with obstructive sleep apnoea (OSA) who were adherent and took on continuous positive airway pressure (CPAP) therapy after a 1-month CPAP trial period continued to be adherent to the therapy at 1 year, indicating that initial receptibility to CPAP is predictive of long-term adherence to the therapy, a local study finds.

Home NIV and HST: Improving quality of care for patients with COPD and OSA

01 Jul 2018

Airway diseases – such as chronic obstructive pulmonary disease and obstructive sleep apnoea – have a significant impact on one’s health, quality of life and daily functioning. This article discusses how technological advancements in non-invasive ventilation and home sleep testing systems help to improve patient care and outcomes.

Contemporary management of paediatric respiratory diseases: A novel combo of secretolytic and bronchospasmolytic actions

22 Jan 2018

During the recent 2017 Engelhard-Delfi Conference, organized by Delfi Marketing Sdn Bhd, three renowned speakers shared their insights into paediatric respiratory medicine.

Advancing the treatment paradigm of idiopathic pulmonary fibrosis (IPF)

22 Jan 2018

Literature suggests that IPF is either the first or second most common interstitial lung disease (ILD) in pulmonology practice, with prevalence ranging from 17–86%. At the recent 3rd Respiratory Forum organized by Boehringer Ingelheim, Dr Felix Chua shared his insights into the importance of advancing the treatment paradigm of IPF, and the role of nintedanib (OFEV^®) in its management.

The importance of inhaler devices in the management of asthma and chronic obstructive pulmonary disease

05 Jan 2018

At a recent dinner symposium at Shangri-La Kuala Lumpur, Dr Omar Usmani discussed the importance of inhaler devices in the management of asthma and chronic obstructive pulmonary disease (COPD).

Antihistamine therapy for allergic rhinitis and urticaria: An Asia-Pacific perspective

27 Dec 2017

The prevalence of allergic diseases in the Asia-Pacific region is expected to rise over the next 20 years, driven by rapid economic development and urbanization. Allergic diseases have high socioeconomic impact by impairing productivity and quality of life, and the impact may be greater in Asia-Pacific than in Europe due to the presence and predominance of perennial allergens.

Relvar Ellipta: Is once-daily dosing the practical choice for asthma maintenance?

18 Dec 2017

At a GlaxoSmithKline-sponsored symposium during the Malaysian Thoracic Society Annual Congress 2017, Dr Celeste Mae Lardizabal-Campomanes presented on three key strategies of optimizing asthma treatment.

Unnecessary antibiotics for asthma linked to longer hospital stay, elevated cost

Roshini Claire Anthony, 07 Jun 2018

Prescribing antibiotics despite no indication of infection to patients hospitalized with asthma was associated with longer hospital stay, a higher risk of antibiotic-related diarrhoea, and elevated hospitalization costs, according to a study presented at the recent American Thoracic Society conference (ATS 2018).

Obesity paradox debunked in COPD patients with BMI >40

Elvira Manzano, 05 Jun 2018

The notion that overweight patients with COPD* seems to have a reduced risk of mortality vs those who are of normal weight, or that fat alters outcomes in obese patients – a phenomenon called “obesity paradox” – does not hold true if BMI is >40 kg/m2, a study has shown.

Eczema drug emerges as potential asthma treatment

Roshini Claire Anthony, 04 Jun 2018

Dupilumab, the fully human anti-interleukin-4 receptor α monoclonal antibody indicated for the treatment of atopic dermatitis, appeared to improve lung function, reduce exacerbations, and decrease oral corticosteroid use in individuals with moderate-to-severe asthma, according to two phase III trials presented at ATS 2018.

Vitamin C improves lung function in babies exposed to in-utero smoke

Audrey Abella, 04 Jun 2018

Vitamin C supplementation in pregnant women who smoke resulted in improved forced expiratory flow (FEF*) in their newborns at 3 and 12 months, according to data presented at ATS 2018.

LABA/LAMA combo sufficient for moderate-to-severe COPD?

Roshini Claire Anthony, 02 Jun 2018

De-escalating treatment from triple therapy (LABA*/LAMA**/inhaled corticosteroid [ICS]) to dual bronchodilator therapy (indacaterol/glycopyrronium) did not increase exacerbation rate, though there was a minor decrease in lung function in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) with infrequent exacerbations, according to results of the SUNSET*** trial presented at the recent American Thoracic Society conference (ATS 2018).

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