Respirology



Two target trials were emulated to compare the effectiveness of third doses of mRNA-based COVID-19 vaccines among US veteran population and across at-risk US veteran populations.





Two target trials were emulated to compare the effectiveness of third doses of mRNA-based COVID-19 vaccines among US veteran population and across at-risk US veteran populations.



COVID-19 vaccination can reduce the risk of long COVID if given before SARS-CoV-2 infection.
Findings suggest that vaccination before infection confers only partial protection in the post-acute phase of the disease. Hence, reliance on vaccination as a sole mitigation strategy may not optimally reduce long-term health consequences of SARS-CoV-2 infection.


A retrospective national cohort study in Singapore assessed hybrid immunity from previous infection and monovalent vaccination against medically attended symptomatic BA.4, BA.5, and XBB reinfections.
This study highlights the immune evasiveness of the XBB variants. All human viruses adapt to become more transmissible, more immune evasive, and less virulent over time, and SARS-CoV-2 is no exception.





Treatment with dupilumab significantly improves lung function in children with moderate-to-severe type 2 asthma compared with placebo, according to two post hoc analyses presented at ERS 2023.
