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Top Medical News
While patients on extracorporeal membrane oxygenation (ECMO) appear to enjoy good survival rates, long-term quality of life (QoL) and functional deficits still persist, a recent study has found.
Assoc Prof Philip Eng, senior consultant respiratory physician at Mt Elizabeth Hospital in Singapore, shares his insights with Pearl Toh on diagnosing and managing pneumonia in the primary care setting.
Use of metformin may reduce mortality from chronic lower respiratory disease (CLRD) among adults with diabetes, a new study has found.
Airway closure occurs in patients with asthma in response to methacholine, according to a recent study. In addition, older age and obesity are associated with increased airway closure.
Due to the apparent risk of adverse outcomes of disease and adverse events (AEs) associated with short-acting beta-agonists (SABA), the Global Initiative for Asthma (GINA) 2019 guideline recommends that all patients with mild asthma should receive symptom-driven or regular low-dose inhaled corticosteroid (ICS)−containing controller treatment.
The overall health and process outcomes in asthma appear to have improved in a public primary healthcare institution in Singapore, owing to the adoption of Chronic Care Model (CCM)—a multifaceted model of care aimed at making patients healthier and healthcare providers more satisfied and reducing cost savings, as reported in a recent study.
Long-term treatment with the interleukin-5
receptor alpha-directed cytolytic monoclonal antibody benralizumab led to long-term control of asthma, improvement in pulmonary function, and was safe in patients with severe eosinophilic asthma in the 2-year integrated analysis of the SIROCCO, CALIMA, and ZONDA pivotal studies plus the BORA extension study reported at ATS 2019.
Special Reports
The prevalence of allergic diseases in the Asia-Pacific region is expected to rise over the next 20 years, driven by rapid economic development and urbanization. Allergic diseases have high socioeconomic impact by impairing productivity and quality of life, and the impact may be greater in Asia-Pacific than in Europe due to the presence and predominance of perennial allergens.
At a dinner symposium at Le Méridien Kuala Lumpur, Professor Dato’ Prepageran Narayanan presented the data concerning allergic rhinitis (AR) in Malaysia, and he discussed the role of intranasal corticosteroids (INCSs) in managing AR.
Hypertension guidelines differ in their recommendation to use beta-blockers as first-line agents. At a Menarini-sponsored symposium held during the Asian Pacific Society of Cardiology Congress 2018 in Taipei, Taiwan, Professor Giuseppe Mancia from the University of Milano-Bicocca in Milan, Italy and Professor Jong-Won Ha from the Yonsei University College of Medicine in Seoul, Korea discussed the rationale behind these recommendations, and reviewed the role of beta-blockers in hypertension management, particularly the role of vasodilatory beta-blocker nebivolol (Nebilet®, Menarini). Professor Lin Jiunn-Lee, APSC 2018 chairman and president of the Taiwan Society of Cardiology, chaired the symposium.
Airway diseases – such as chronic obstructive pulmonary disease and obstructive sleep apnoea – have a significant impact on one’s health, quality of life and daily functioning. This article discusses how technological advancements in non-invasive ventilation and home sleep testing systems help to improve patient care and outcomes.
SPIOLTO RESPIMAT - Tiotropium 2.5 mcg, Olodaterol 2.5 mcg inhalation soln - Boehringer Ingelheim
During the recent 2017 Engelhard-Delfi Conference, organized by Delfi Marketing Sdn Bhd, three renowned speakers shared their insights into paediatric respiratory medicine.
Literature suggests that IPF is either the first or second most common interstitial lung disease (ILD) in pulmonology practice, with prevalence ranging from 17–86%. At the recent 3rd Respiratory Forum organized by Boehringer Ingelheim, Dr Felix Chua shared his insights into the importance of advancing the treatment paradigm of IPF, and the role of nintedanib (OFEV®) in its management.
Conference Reports
Long-term treatment with the interleukin-5
receptor alpha-directed cytolytic monoclonal antibody benralizumab led to long-term control of asthma, improvement in pulmonary function, and was safe in patients with severe eosinophilic asthma in the 2-year integrated analysis of the SIROCCO, CALIMA, and ZONDA pivotal studies plus the BORA extension study reported at ATS 2019.
Use of the novel application (app) CureApp Smoking Cessation (CASC) results in a significantly higher continuous abstinence rate (CAR) from weeks 9 to 24 compared to the control app, making it a promising tool for smoking cessation treatment, according to a study presented at the American Thoracic Society (ATS) 2019 International Conference.
The reduced mortality/morbidity benefit previously demonstrated with selexipag in patients with pulmonary arterial hypertension (PAH) may be more pronounced when treatment is initiated soon after diagnosis, according to results of a post hoc analysis of the GRIPHON* study presented as a poster at ATS 2019.
Diagnosis of gastro-oesophageal reflux disease (GERD) remains unclear in patients with subacute/chronic cough, especially those with low blood eosinophil counts ≤150/μl, but using the Frequency Scale for the Symptoms of GERD (FSSG) questionnaire may considerably help, suggests a study presented at the recent American Thoracic Society (ATS) 2019 International Conference held at Dallas, Texas in the US.
Treatment with dupilumab, a fully human monoclonal antibody that inhibits interleukin (IL)-4 and IL-13 signalling, significantly reduces severe exacerbation rate and improves lung function in patients with late-onset asthma, according to results of a post hoc analysis of the Liberty Asthma Quest* trial presented at ATS 2019.
Slideshow: Highlights from the American Thoracic Society 2019 (ATS 2019) International Conference
Podcast: Professor Oliver Distler talks about the utility of nintedanib in ILD in the SENSCIS trial
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