Adverse childhood experiences (ACEs) may have intergenerational consequences, a new study suggests. Children born to mothers with chronic pain and with histories of ACEs are more likely to have depressive symptoms.
Patients with axial spondyloarthritis (axSpA) are at increased risk of mental disorders, suggests a recent study. High disease activity, combined with a certain sociodemographic profile, is a good indicator of such risk.
Individuals with attention-deficit hyperactivity disorder (ADHD) are likely to exhibit suicidal behaviour, and this probability is further increased in the presence of comorbid psychiatric disorders, a recent study suggests.
Routine prescription of a hypnotic medication does not appear to substantially reduce suicidal ideation in depressed outpatients with insomnia, but coprescription of such drug during antidepressant initiation may help suicidal outpatients, particularly those with severe insomnia, suggest the results of a study.
Specific functional network-based moderators of treatment outcome have been identified, and these involve brain networks affected by major depression, reports a study. In addition, a favourable response for an antidepressant medication appears to be influenced by functional connectivity patterns of brain regions between and within networks.
Depressive symptoms appear to be common in middle aged and older Chinese adults, particularly in women and those residing in rural areas, according to a secondary analysis of a prospective cohort study. On the other hand, longer sleep duration and better self-perceived health status confer protective benefits.
Generalized anxiety symptoms commonly occur after stroke or transient ischaemic attack and are associated with younger age and greater depressive symptoms, and these relationships persist even among patients without severe comorbid depressive symptoms, as reported in a recent study.
Mental health smartphone applications (apps) help improve a range of outcomes, including depressive and generalized anxiety symptoms and stress levels, with small-to-moderate effect sizes, according to a meta-analysis.
Several anti-inflammatory drugs, including aspirin, oestrogens, minocycline and N-acetylcysteine, appear to help mitigate symptom severity in patients with schizophrenia, according to a systematic review and meta-analysis.
Individuals with obsessive–compulsive disorder (OCD) with a chronic illness course are at greater risk of remaining chronic, which, in turn, is associated with poor clinical outcome, according to a study.