Prostatitis is the inflammation of the prostate that may be caused by infection, chronic pelvic pain syndrome or asymptomatic prostate inflammation.
Prominent features are genitourinary, pelvic or rectal pain and lower urinary tract symptoms, eg urinary frequency, urgency, hesitancy, weak stream and straining on urination, dysuria, pain that increased with urination.
A spectrum of disorders that affect men whose symptoms are referable to the lower urogenital tract & perineum
Etiologic agents are the same for both acute bacterial prostatitis (ABP) & chronic bacterial prostatitis (CBP) & include E coli (most commonly isolated pathogen), Enterococcus sp, Klebsiella sp, Proteus sp, P aeruginosa, C trachomatis, U urealyticum, T vaginalis
Immune-deficient or human immunodeficiency virus (HIV) patients may have pathogens such as S typhi, M avium, M tuberculosis, Candida sp, C immitis, B dermatitidis, H capsulatum
Signs and Symptoms
Prominent features are genitourinary, pelvic or rectal pain & lower urinary tract symptoms, eg urinary frequency, urgency, hesitancy, weak stream & straining on urination, dysuria, pain that increased w/ urination
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
The selective serotonin reuptake inhibitor escitalopram holds promise in the prevention of Alzheimer’s disease, reducing amyloid-β-42 levels in cerebrospinal fluid and brain tissue in older adults with normal cognitive function, according to recent evidence.
Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.