Oncology Search
Oncology Oncology
prostate%20cancer
PROSTATE CANCER

Prostate cancer is the cancer that occurs in the male's prostate.

It is the most common cancer in men >50 years of age.

Signs and symptoms include weak urinary stream, polyuria, nocturia, hematuria, erectile dysfunction, pelvic pain, back pain, chest pain, lower extremity weakness or numbness and loss of bowel or bladder control.

Introduction

  • One of the most common cancers in men >50 years of age 

Signs and Symptoms

  • Weak urinary stream
  • Polyuria, nocturia
  • Hematuria
  • Erectile dysfunction
  • Pelvic pain, back pain, chest pain
  • Lower extremity weakness or numbness
  • Loss of bladder or bowel control

Risk Factors

  • Age (increased risk in men >50 years old)
  • Positive family history (1st-degree relatives and relatives diagnosed with prostate cancer at an early age doubles the risk)
  • Ethnicity (African-American, Caribbean men of African ancestry)
  • Chemical exposures (toxic combustion products)
  • Genetic mutations: Breast cancer susceptibility gene 1 (BRCA1), breast cancer susceptibility gene 2 (BRCA2) mutations, deoxyribonucleic acid (DNA) mismatch repair genes [MutS Homolog 2 (MSH2), MutL Homolog 1 (MLH1), Lynch syndrome], insulin-like growth factor-1 (IGF-1)
  • Other risk factors under research include a positive medical history of inflammation of the prostate gland [eg prostatitis, STDs, proliferative inflammatory atrophy (PIN)] and vasectomy
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Oncology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Highlights from ESMO Asia 2017: Moving to a dual blockade strategy early in hormone receptor-positive breast cancer
22 Jan 2018
In a symposium chaired by Dr Yoon-Sim Yap of the National Cancer Centre Singapore, renowned regional and international experts in the field of breast cancer, Dr Yen-Shen Lu from Taiwan and Professor Nadia Harbeck from Germany, joined her in providing insights on the current treatment landscape of hormone receptor-positive (HR+) advanced breast cancer. In their respective sessions, they each highlighted new therapeutic options including the optimal use of dual blockade therapy for oestrogenreceptor-positive (ER+) advanced breast cancer for patients in Asia. 
Highlights from the Joint Cancer Genetics Meeting and the 15th International Meeting on the Psychosocial Aspects of Hereditary Cancer (IMPAHC) 2017
Dr Joslyn Ngu, 23 Nov 2017
Highlights from the Joint Cancer Genetics Meeting and the 15th International Meeting on the Psychosocial Aspects of Hereditary Cancer (IMPAHC) 2017