primary%20angle-closure%20glaucoma
PRIMARY ANGLE-CLOSURE GLAUCOMA
Primary angle-closure is the synechial or appositional closure of the anterior chamber angle secondary to multiple mechanisms resulting in raised intraocular pressure and structural changes in the eyes.
Iridotrabecular contact is the hallmark of primary angle-closure  and the most commonly identified sign which indicates that treatment is required.
It is defined by at least 180 degrees of iridotrabecular contact together with an elevated intraocular pressure or peripheral anterior synechiae or btoh
Primary angle-closure glaucoma is the presence of glaucomatous optic neuropathy.
  1. Canadian Ophthalmological Society Glaucoma Clinical Practice Guideline Expert Committee; Canadian Ophthalmological Society. Canadian Ophthalmological Society evidence-based clinical practice guidelines for the management of glaucoma in the adult eye. Can J Ophthalmol. 2009;44(Suppl Suppl 1):S7-S93. doi: 10.3129/cjo44s1. Accessed 10 Feb 2012. PMID: 19492005
  2. Broan AM, Garcger CP, Sirbat D, et al. Comparison of two fixed beta-blocker-pilocarpine combinations. The Carteolol-Pilocarpine Study Group. Eur J Ophthalmol. 1997;7(4):351-356. Accessed 10 Feb 2012. PMID: 9457458
  3. Demailly P, Allaire C, Bron V, Trinquand C. Effectiveness and tolerance of beta blocker/pilocarpine combination eye drops in primary open-angle glaucoma and high intraocular pressure. J Glaucoma. 1995 Aug;4(4):235-241. Accessed 10 Feb 2012. PMID: 19920680
  4. European Glaucoma Society. Terminology and guidelines in glaucoma. 3rd. Italy: European Glaucoma Society; 2008.
  5. South East Asia Interest Group. Asia Pacific glaucoma guidelines. 2nd ed. Sydney, Australia: SEAGIG; 2008
  6. See JL, Chew PTK. Angle-closure glaucoma. In: Yanoff M, Duker JS, et al. Ophthalmology. 3rd ed. Maryland Heights, MO: Mosby, Elsevier; 2009:1162-1171
  7. International Council of Ophthalmology. Primary angle closure (initial evaluation and therapy). International Council of Ophthalmology. http://www.icoph.org/dynamic/attachments/resources/icopriangleclosure_2.pdf. 2010. Accessed 28 Aug 2012.
  8. American Academy of Ophthalmology Glaucoma Panel. Preferred Practice Pattern Guidelines. Primary angle closure. San Francisco, CA: American Academy of Ophthalmology. http://one.aao.org/preferred-practice-pattern/primary-angle-closure-ppp--october-2010. 2010. Accessed 22 Aug 2012
  9. Japan Glaucoma Society. Guidelines for glaucoma. 2nd ed. Japan Glaucoma Society. http://ryokunaisho.jp/. Sep 2006. Accessed 31 Aug 2012.
  10. American Optometric Association. Primary angle closure glaucoma. http://www.aoa.org/. 1998. Accessed 03 Sep 2012.
  11. National Collaborating Centre for Acute Care. Glaucoma: Diagnosis and management of chronic open angle glaucoma and ocular hypertension. National Institute for Health and Care Excellence. http://www.nice.org.uk/. Apr 2009. Accessed 03 Feb 2012.
  12. Cheng JW, Zong Y, Zeng YY, et al. The prevalence of primary angle closure glaucoma in adult Asians: a systematic review and meta-analysis. PLoS One. 2014 Jul 24;9(7):e103222. doi: 10.1371/journal.pone.0103222. Accessed 22 Sep 2015. PMID: 5057993
  13. Emanuel ME, Parrish RK 2nd, Gedde SJ. Evidence-based management of primary angle closure glaucoma (abstract). Curr Opin Ophthalmol. 2014 Mar;25(2):89-92. doi: 10.1097/ICU.0000000000000028. Accessed 24 Sep 2015. PMID: 24463418
  14. Muñoz-Negrete FJ, González-Martín-Moro J, Casas-Llera P, et al. Guidelines for treatment of chronic primary angle-closure glaucoma. Arch Soc Esp Oftalmol. 2015 Mar;90(3):119-138. doi: 10.1016/j.oftal.2014.09.014. Accessed 22 Sep 2015. PMID: 25459683
  15. Weizer JS. Angle-closure glaucoma. UpToDate. https://www.uptodate.com. Dec 2018. Accessed 22 Sep 2015.
  16. Jacobs DS. Open-angle glaucoma: treatment. UpToDate. https://www.uptodate.com. 23 Apr 2019. Accessed 12 Oct 2015.
  17. European Glaucoma Society (EGS). Terminology and guidelines for glaucoma. 4th ed. EGS. http://www.eugs.org/eng/EGS_guidelines4.asp. Jun 2014.
  18. Asian Pacific Glaucoma Society. Asia Pacific glaucoma guidelines. APGS. 3rd ed. Amsterdam: Kugler Publications; 2016.
  19. Gross RL, McMillan BD. Current medical management of glaucoma. In: Yanoff M, Duker JS, eds. Ophthalmology. 5th ed. Philadelphia, Pennsylvania, USA: Saunders, Elsevier; 2019. 1120-1125. :1120-1125.
  20. International Council of Ophthalmology (ICO). ICO guidelines for glaucoma eye care. ICO. http://www.icoph.org. 2015.
  21. Lee DA, Higginbotham EJ. Glaucoma and its treatment: a review. Am J Health Syst Pharm. 2005 Apr;62(7):691-699. doi: 10.1093/ajhp/62.7.691. PMID: 15790795
  22. Lusthaus J, Goldberg I. Current management of glaucoma. Med J Aust. 2019 Mar;210(4):180-187. doi: 10.5694/mja2.50020. PMID: 30767238
  23. MacIver S, MacDonald D, Prokopich CL. Screening, diagnosis, and management of open angle glaucoma: an evidence-based guideline for Canadian optometrists. Can J Optometry. 2017;79(Suppl 1).
  24. Ministry of Health Malaysia. Clinical practice guideline: management of glaucoma (2nd edition). http://www.acadmed.org.my. Jun 2017.
  25. National Health and Medical Research Council. NHMRC guidelines for the screening, prognosis, diagnosis, management and prevention of glaucoma 2010. NHMRC. https://www.nhmrc.gov.au. 2010.
  26. National Institute for Health and Care Excellence (NICE). Glaucoma: diagnosis and management. NICE. http://www.nice.org.uk. 01 Nov 2017.
  27. Optometry Australia. Clinical practice guidelines for the diagnosis, treatment and management of glaucoma. https://www.optometry.org.au. Jul 2016.
  28. Wyeth Pharmaceuticals. Phospholine iodide (echothiophate) [prescribing information]. www.dailymed.nlm.nih.gov. Jul 2018.
  29. Prum BE Jr, Rosenberg LF, Gedde SJ, et al. Primary open-angle glaucoma preferred practice pattern guidelines. Ophthalmology. 2016 Jan;123(1):P41-P111. doi: 10.1016/j.ophtha.2015.10.053. PMID: 26581556
  30. Azuara-Blanco A, Burr J, Ramsay C, et al. Effectiveness of early lens extraction for the treatment of primary angle-closure glaucoma (EAGLE): a randomized controlled trial. Lancet. 2016 Oct;388(10052):1389-1397. doi: 10.1016/S0140-6736(16)30956-4. PMID: 27707497
  31. Khondkaryan A, Francis BA. Angle closure glaucoma. American Academy of Ophthalmology. https://www.aao.org. Dec 2013.
  32. Lim DKA, Koh VTC, Aquino MC, et al. Angle-closure glaucoma. In: Yanoff M, Duker JS, eds. Ophthalmology. 5th ed. Philadelphia, Pennsylvania, USA: Saunders, Elsevier; 2019. 1064-1073. :1064-1073.
  33. Prum BE Jr, Herndon LW Jr, Moroi SE, et al. Primary angle closure preferred practice pattern guidelines. Ophthalmology. 2016 Jan;123(1):P1-P40. doi: 10.1016/j.ophtha.2015.10.049. PMID: 26581557
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