Premature ejaculation is a male sexual dysfunction characterized by short, easily stimulated ejaculation that occurs always or nearly always before or within one minute of vaginal penetration.
It is involuntarily controlled and causes negative personal consequences like distress, frustration and avoidance of sexual intimacy.
Exact etiology and risk factors are unknown.
Althof SE, Abdo CH, Dean J, et al. International Society for Sexual Medicine’s guidelines for the diagnosis and treatment of premature ejaculation. J Sex Med. 2010 Sep;7(9):2947-2969. doi: 10.1111/j.1743-6109.2010.01975.x. PMID: 21050394
Althof SE, McMahon CG, Waldinger MD, et al. An update of the International Society of Sexual Medicine’s guidelines for the diagnosis and treatment of premature ejaculation. J Sex Med. 2014 Jun;11(6):1392-1422. doi: 10.1111/jsm.12504. PMID: 24848686
Hatzimouratidis K, Amar E, Eardley I, et al. European Association of Urology guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation. European Urology. 2010;57:804-814. doi: 10.1016/j.eururo.2010.02.020. PMID: 20189712
Hatzimouratidis K, Eardley I, Giuliano F, et al. European Association of Urology guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation. 2015 Mar:1-53.
Montague DK, Jarow J, Broderick GA, et al. American Urological Association guideline on the pharmacologic management of premature ejaculation.. J Urol. 2004 Jul;172(1):290-294. http://www.auanet.org/content/clinical-practice-guidelines/clinical-guidelines/main-reports/pme/pme_2004.pdf. PMID: 15201797
Society for Men’s Health (Singapore). MIMS guidelines on premature ejaculation by Society for Men’s Health (Singapore). MIMS; 2014:1-9.
Symonds T, Perelman MA, Althof S, et al. European Association of Urology development and validation of a premature ejaculation diagnostic tool. Eur Urol. 2007 Aug;52(2):565-573. http://www.ncbi.nlm.nih.gov/pubmed/17275165. PMID: 17275165
Hatzimouratidis K, Salonia A, Giuliano, et al. European Association of Urology guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation. UroWeb. www.uroweb.org. 2017.
El-Hamd MA, Saleh R, Majzoub A. Premature ejaculation: an update on definition and pathophysiology. Asian J Androl. 2019 Mar. doi: 10.4103/aja.aja_122_18. PMID: 30860082
Chung E, Gilbert B, Perera M, et al. Premature ejaculation: a clinical review for the general physician. Aust Fam Physician. 2015 Oct;44(10):737-743. PMID: 26484490
Hatzimouratidis K, Guiliano F, Moncada I, et al. EAU guidelines on erectile dysfunction, premature ejaculation, penile curvature and priapism. European Association of Urology. https://uroweb.org. Mar 2016.
Khera M, Cunningham GR. Treatment of male sexual dysfunction. UpToDate. https://www.uptodate.com. Oct 2018. Accessed 24 Jul 2019.
While most patients do not have such concerns, some young men treated for testicular cancer experience sexual dysfunction and other reproductive concerns 2 years after diagnosis, a recent study has found.
Coadministration of DHA and vitamin E supplements results in increased sperm motility, but no significant changes have been observed in sperm morphology and vitality in asthenozoospermic men, a study has shown.