Polycystic ovarian syndrome (PCOS) is the accumulation of underdeveloped follicles in the ovaries due to anovulation. It is is characterized by menstrual abnormalities and clinical or biochemical features of hyperandrogenism.
It results mainly from abnormal steroidogenesis that may be caused by insulin resistance leading to hyperinsulinemia.
There is increased sensitivity to androgens and the majority of women have elevated androgen levels.
A small cohort study presented at the Royal College of Obstetricians & Gynaecologists (RCOG) World Congress 2018 has reported a 5-year diabetic ketoacidosis (DKA) incidence rate of 4.16 percent in pregnant women with type 1 diabetes mellitus (T1DM), with generally good maternal and neonatal outcomes.
Dietary glycaemic index (GI) or glycaemic load (GL) does not appear to have any significant effect on serum concentrations of inflammatory cytokines, including high-sensitivity C-reactive protein (hs-CRP), leptin, interleukin 6 (IL-6) and tumour necrosis factor α (TNF-α) in adults, reports a new study.