pheochromocytoma
PHEOCHROMOCYTOMA
Pheochromocytoma is a rare adrenal gland tumor that may precipitate life-threatening hypertension.
It can occur at any age but usually occurs during young to mid-adult life.
Majority of patients presents with ≥1 of the following hypertension resistant to standard antihypertensive treatment, hypertensive crisis with malignant hypertension, hypertensive encephalopathy, aortic dissection, or myocardial infarction and paroxysmal symptoms which suggest seizure disorder, anxiety attacks or hyperventilation.

Surgical Intervention

  • Treatment of choice for most cases of pheochromocytoma
  • Should be performed in experienced centers
  • It is microscopically difficult to determine if pheochromocytoma is malignant
  • Each pheochromocytoma should be regarded as potentially malignant during surgery
    • The entire gland & the surrounding tissues must be removed to prevent recurrence of local disease
  • Preoperative pharmacologic management involves alpha & beta adrenergic blockade to control blood pressure & prevent hypertensive crisis during the surgical procedure
    • A high-sodium diet w/ increased fluid intake is recommended pre-op to prevent post-operative volume depletion
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