Adding nivolumab to chemotherapy in the first-line setting significantly improves survival compared with chemotherapy alone in patients with HER2-negative advanced gastric/gastroesophageal (G/GEJ) cancer or oesophageal adenocarcinoma (EAC), shows the CheckMate 649 study presented at ESMO 2020.
Initiating COVID-19 patients with type 2 diabetes on sitagliptin at the time of hospitalization appears to reduce mortality and improve clinical outcomes as compared with administering standard-of-care treatment alone, a study has found.
Treatment with famotidine in hospitalized patients with the novel coronavirus disease (COVID-19) may help reduce the risk of death, results of a study have shown. It is also associated with a lower risk of the combined outcome of mortality and intubation, as well as decreased levels of serum markers for those with severe disease.
Aspirin appears to exert protective effects in patients with the novel coronavirus disease (COVID-19) by reducing the risk of death and the need for intensive care or mechanical ventilation, according to a recent study.
Quadrivalent human papillomavirus (HPV) vaccination can substantially reduce the risk of invasive cervical cancer, by up to almost 90 percent in women who were vaccinated early, a large Swedish registry-based study has shown.
Olaparib, a PARP* inhibitor used to treat ovarian and breast cancer, also extends overall survival (OS) of men with metastatic castration-resistant prostate cancer (mCRPC) harbouring at least one mutation in BRCA1, BRCA2, or ATM, according to final report of the PROfound** study presented at ESMO 2020.
Osteoarthritis (OA) is the most common condition affecting the joints. Dr Lee Eu Jin, an Orthopaedic Surgeon from Liberty Orthopaedic Clinic at Mount Elizabeth Medical Centre, Singapore, shares his insights with Pearl Toh on how to manage OA in the primary care setting.
The use of aspirin for primary prevention in patients without known cardiovascular diseases (CVDs) significantly reduces the risk of myocardial infarction (MI) but increases that of major bleeding and haemorrhagic stroke, according to a meta-analysis.