Treatment with brolucizumab results in a longer interval between injections of antivascular endothelial growth factor (anti-VEGF) agents for most treatment-experienced eyes, especially those with shorter intervals before switching, while maintaining or improving visual acuity (VA), reports a study.
A machine learning model that incorporates artificial intelligence (AI) techniques to predict the blood concentration of quetiapine is feasible for clinical medication guidance in patients with schizophrenia and depression, reports a real-world study.
Misoprostol, a prostaglandin E1 analogue used to prevent nonsteroidal anti-inflammatory drug (NSAID)-related gastrointestinal disorders, appears effective in preventing kidney injury associated with chronic NSAID use, but the quality of evidence is very low, results of a recent study have shown.
For patients with venous thromboembolism (VTE) who are prescribed to undergo anticoagulation beyond 6 months, continued direct oral anticoagulant (DOAC) treatment is associated with a lower risk of VTE recurrence compared with continued warfarin, as reported in a study.
Several cancer patients have benefitted from nonstandard of care (non-SOC) recommendations by the regional precision medicine molecular tumour board (PMMTB), reports a study. Also, additional processes have been implemented to improve the accessibility of non-SOC treatment.
A recent study has observed a low incidence of antibiotic-associated diarrhoea (AAD) among hospitalized children with no comorbid disease. In addition, most episodes of diarrhoea are mild and self-limiting, occurring usually among male patients, those aged <3 years, and those treated with ibuprofen.
In patients with focal epilepsy, seizure frequency at baseline and the number of previous antiseizure medications (ASMs) used can predict sustained reduction in seizure frequency with adjunctive brivaracetam, according to data from the BRIVAFIRST study.
For pregnant women at risk of delivering preterm, intravenous administration of magnesium sulfate prior to preterm birth at 30–34 week of gestation does not appear to minimize the chances of child survival free of cerebral palsy at 2 years, as shown in a study.