Use of swallowed topical corticosteroids in the maintenance setting appears to increase the probability of achieving complete remission in eosinophilic esophagitis (EoE) as compared with nonuse, a study has found.
In patients with type 2 diabetes (T2D), sodium-glucose cotransporter 2 (SGLT2) inhibitor monotherapy, particularly canagliflozin, exerts greater effects on weight compared with metformin and dipeptidyl peptidase 4 (DPP-4) inhibitors or gliptins, according to the results of a meta-analysis.
N-acetylcysteine (NAC), sodium bicarbonate, ascorbic acid and statins appear to effectively prevent contrast-induced acute kidney injury in patients with chronic kidney disease undergoing coronary angiography with or without percutaneous coronary intervention, according to a meta-analysis. Evidence is strongest for NAC, especially in patients requiring high-contrast doses.
Intravitreal triamcinolone acetonide (ITA) and intravitreal dexamethasone implant (IDI) are better than periocular triamcinolone acetonide (PTA) in the treatment of uveitic macular oedema (ME), with modest increases in risk of intraocular pressure (IOP), suggests a study. Such risk does not significantly differ between intravitreal treatments.
RPC4046, a monoclonal antibody against interleukin (IL)-13, safely and effectively reduces histologic and endoscopic features in patients with eosinophilic oeosophagitis (EoE), a recent phase II trial has shown.
Guanfacine and computerized cognitive remediation therapy plus social skills training are both well tolerated in patients with schizotypal personality disorder (SPD), with no side effects or dropouts, a recent study has shown.
Olanzapine confers a modest therapeutic effect on weight compared with placebo in adult outpatients with anorexia nervosa, a study has shown. However, it does not appear to offer significant benefit for psychological symptoms.
The in-use stability of rituximab biosimilar Rixathon/Riximyo is not affected by dilution and formulation conditions needed for intravenous infusion even under worst case condition in terms of product shelf life, temperature excursion, light exposure, dilution factor and infusion bag storage time over a period of 31 days, according to biological and physicochemical analyses of a recent study.
A latest study at ISC 2019 shows that even patients with large-core stroke damage can have a good outcome after mechanical clot removal with endovascular thrombectomy (EVT), depending on the size of the infarct and time lapses between stroke onset and treatment.
Supplementation with omega-3 fatty acids in combination with rosuvastatin may yield significant reductions in triglycerides and nonhigh-density lipoprotein (HDL) cholesterol as compared with rosuvastatin monotherapy, according to data from the ROMANTIC (rosuvastatin-omacor in residual hypertriglyceridemia) trial.
Roshini Claire Anthony spoke with Adjunct Associate Professor Gamaliel Tan, head and senior orthopaedic consultant at Ng Teng Fong Hospital in Singapore, on how GPs can help diagnose and treat lower back pain.