Use of eslicarbazepine acetate over the long term in the treatment of patients with focal epilepsy appears to be well tolerated and induces freedom from seizures, according to the results of an open-label study.
Romilkimab, a novel bispecific immunoglobulin-G4 antibody that binds and neutralizes interleukin (IL)-4/IL-13, shows promise in the treatment of diffuse cutaneous systemic sclerosis, producing significant reduction in skin fibrosis, according to the results of a phase II trial.
Women with high levels of very low-density lipoprotein cholesterol or high apolipoprotein B to A-1 ratio may fare better with insulin than metformin, with a recent study showing that treatment with the latter leads to higher serum concentrations of triglyceride-rich lipoproteins in the last trimester of pregnancy.
In the treatment of schizophrenia, patients on typical antipsychotics have better memory than those taking clozapine or risperidone, and patients on clozapine have better language function compared with those on risperidone, as shown in a study.
Prophylactic use of the antifibrinolytic agent tranexamic acid results in less bleeding during transbronchial biopsies, allowing more specimens to be obtained with no additional adverse events, a study has found.