Use of pegylated interferon alpha 2a as an add-on therapy in chronic hepatitis B patients on tenofovir disoproxil fumarate facilitates rapid reductions in hepatitis B surface antigen (HBsAg) and core-related antigen (HBcrAg) levels, a study has shown.
Current use of antidepressants interfering selectively with the reuptake of serotonin and those antagonizing the 5‐HT2A receptor results in a reduced risk of acute myocardial infarction (AMI), a recent study has shown.
Using the standard American Urological Association (AUA) antibiotic prophylaxis for penile prosthesis surgery among diabetic men with erectile dysfunction results in significantly higher likelihood of postoperative device infection and device explantation compared with nonstandard prophylaxis, suggests a recent study.
Intraperitoneal therapy with paclitaxel and cisplatin does not result in longer progression-free or overall survival in the adjuvant setting among patients with stage III ovarian cancer as compared with dose-dense paclitaxel and carboplatin, results of a study have shown. In addition, tolerability appears to have decreased with intraperitoneal therapy.
In the treatment of cytokine storm syndrome due to the coronavirus disease (COVID-19), administering tocilizumab via the intravenous (IV) route appears to be more effective than subcutaneous (SC) therapy, leading to earlier symptom improvement and better survival, according to a study.
Use of rivaroxaban, with or without aspirin, falls short of reducing the number of incident covert infarcts compared with aspirin alone in patients with stable coronary and peripheral vascular disease, according to a study.
Use of methimazole appears to elevate the risk of acute pancreatitis (AP), a recent study has found. This supports the warning issued by the European Medicine Agency (EMA) regarding a potential increased risk of AP in users of methimazole.
Use of eslicarbazepine acetate over the long term in the treatment of patients with focal epilepsy appears to be well tolerated and induces freedom from seizures, according to the results of an open-label study.
Interim results of REGENERATE* trial highlight the ability of experimental noninvasive tests to evaluate treatment response in adults with NASH** and advanced liver fibrosis who are receiving obeticholic acid (OCA).
The combination of pitavastatin and fenofibrate appears to have superior effect on non-high-density lipoprotein cholesterol (non–HDL-C), as well as other lipids, compared with a statin alone in high-risk patients with mixed dyslipidemia, according to a study.
The use of aspirin for primary prevention in patients without known cardiovascular diseases (CVDs) significantly reduces the risk of myocardial infarction (MI) but increases that of major bleeding and haemorrhagic stroke, according to a meta-analysis.