Two rivaroxaban regimens combined with either a P2Y12 inhibitor or dual antiplatelet therapy (DAPT) reduced bleeding vs a combination of vitamin K antagonist (warfarin) and DAPT in patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) with stenting, the PIONEER AF-PCI* has shown.
The addition of evolocumab to statin therapy in individuals with angiographic coronary disease appeared to encourage coronary atherosclerosis regression, as demonstrated in the GLAGOV* trial presented at the Scientific Sessions of the American Heart Association (AHA 2016) held in New Orleans, Louisiana, US.
Moderate doses of celecoxib are noninferior to naproxen or ibuprofen in terms of cardiovascular (CV) safety, according to results of the PRECISION* trial presented at the Scientific Sessions of the American Heart Association held recently in New Orleans, Louisiana, US.
Intravenous ferric carboxymaltose appears to produce a significant improvement in exercise capacity, as measured by peak oxygen consumption (VO2), in symptomatic patients with heart failure (HF) and iron deficiency, according to the results of the EFFECT-HF trial presented at the American Heart Association (AHA) 2016 Scientific Sessions.
Ticagrelor is not superior to clopidogrel in reducing cardiovascular events in patients with symptomatic peripheral artery disease (PAD), according to primary results of the EUCLID* trial presented at the Scientific Sessions of the American Heart Association held recently in New Orleans, Louisiana, US.
Post-percutaneous coronary intervention (PCI) patients with the loss-of-function variant of the CYP2C19 gene are at a higher risk of major adverse cardiac events (MACE) if they were prescribed clopidogrel instead of alternative anti-platelet therapies, according to a study presented at the American Heart Association Scientific Sessions 2016.
A heart failure monitoring solution that features a multi-sensor algorithm has shown compelling performance in detecting impending heart failure events (HFEs) in patients with implanted devices, providing a timely alert and thereby an opportunity for interventional treatment, according to the results of the MultiSENSE study presented at the American Heart Association (AHA) 2016 Scientific Sessions.
Allogeneic mesenchymal stem cell therapy presented high safety, tolerability and efficacy in non-ischaemic dilated cardiomyopathy patients, according to the results of the POSEIDON-DCM trial presented at the American Heart Association Scientific Sessions 2016.
Blood pressure lowering medications and statins do not prevent cognitive and functional decline in elderly patients, according to results of the HOPE-3 trial* presented at the Scientific Sessions of the American Heart Association (AHA 2016) held recently in New Orleans, Louisiana, US.
Infusions of recombinant apolipoprotein A-1 (apoA-1) Milano, a high-density lipoprotein (HDL) mimetic containing apoA-1, did not produce significant regression of coronary atherosclerosis in acute coronary syndrome (ACS) patients as assessed by intravascular ultrasound (IVUS) despite promising data from previous trials, according to final data from the MILANO-PILOT* trial presented at the American Heart Association 2016 Scientific Sessions (AHA 2016) held recently in New Orleans, Louisiana, US.
A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated.
Pearl Toh spoke with Dr Teh Ming Ming, senior consultant at the Department of Endocrinology, Singapore General Hospital (SGH), on the major challenges of diagnosing and managing diabetes in primary care, in conjunction with the World Diabetes Day on 14 November. Awareness of the symptoms of diabetes is important, and patients should be empowered to manage their conditions.
New drug applications approved by US FDA as of 1 - 15 June 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.