An intensive blood pressure (BP) reduction approach to keep systolic BP (sBP) at 130 mm Hg may delay the development of subcortical microvascular disease of the brain in hypertensive elderly individuals, thus preserving brain function and preventing cognitive decline, according to the results of the INFINITY* trial presented at ACC 2019. A more aggressive BP-lowering approach also reduced the odds of major cardiovascular (CV) events.
The cardiovascular (CV) benefits of the SGLT2* inhibitor dapagliflozin extend across a broad spectrum of patients with type 2 diabetes (T2D) and high CV risk, in particular those with heart failure with reduced ejection fraction (HFrEF), reports a subanalysis of the DECLARE-TIMI 58 trial presented at ACC.19 Annual Scientific Session.
Performing computed tomography (CT) scans prior to cancer treatment can provide information about coronary artery calcification (CAC), a risk marker for cardiovascular disease (CVD), but this evidence is not always reported and rarely acted upon clinically, according to a study presented at the American College of Cardiology’s 68th Annual Scientific Session (ACC 2019).
Early, in-hospital initiation of sacubitril/valsartan appeared to be a better strategy than enalapril switched to sacubitril/valsartan 8 weeks after randomization in patients with acute decompensated heart failure with reduced ejection fraction (HFrEF), the 4-week, open-label PIONEER-HF extension study has shown.
Implantation of a CardioMEMS-HF* device, an ambulatory haemodynamic monitor with an implantable pulmonary artery pressure (PAP) sensor, led to a reduction in hospital admissions among patients with HF, according to results of the CardioMEMS** study presented at ACC.19.
Regardless of the burden of cardiovascular disease (CVD) risk factors, higher fitness improves survival in elderly adults, according to a new study presented at the recently concluded 68th Annual Scientific Session of the American College of Cardiology (ACC 2019).
Watching too much television and skipping breakfast promote cholesterol plaque buildup in the arteries of the heart. On the other hand, hitting the off button on the TV, leaving the couch and eating a high-energy breakfast act protectively against atherosclerosis and offer substantial benefits in terms of heart health, according to data from the Corinthia epidemiological study presented at the American College of Cardiology Annual Scientific Session 2019.
Use of a smartphone app to monitor blood pressure (BP) remotely, get tips on healthful living and connect with a health coach results in a significant decline in BP within 6 weeks among individuals with both type 2 diabetes (T2D) and uncontrolled hypertension, according to a study presented at the American College of Cardiology’s 68th Annual Scientific Session (ACC 2019).
Several strategies have been proposed to help manage the adverse events (AEs) that emerged during the BEACON CRC trial which assessed the effect of encorafenib plus cetuximab in patients with BRAF V600E mutant metastatic colorectal cancer (mCRC) who had progressed after one or two prior regimens.