Genotype-guided choice of dual antiplatelet therapy just missed significance in reducing ischaemic events in patients with acute coronary syndrome and stable coronary artery disease who underwent percutaneous coronary intervention (PCI), according to the results of the two-arm, parallel, open-label, international, multicentre, randomized superiority TAILOR PCI trial presented at the American College of Cardiology 2020/World Congress of Cardiology (ACC.20/WCC) virtual meeting.
Catheter-based renal denervation (RDN), used without antihypertensive medications, significantly lowers blood pressure (BP) in patients with uncontrolled hypertension without major adverse events (AEs), according to results of the SPYRAL HTN-OFF MED Pivotal trial presented at the American College of Cardiology and World Congress of Cardiology virtual meeting (ACC.20/WCC).
Higher dietary protein intake was associated with a lower risk of developing atrial fibrillation (AF) in postmenopausal women compared with lower protein intake, according to a secondary analysis presented at the ACC.20/WCC Virtual Meeting.
In patients on long-term oral anticoagulant (OAC) therapy who are undergoing transcatheter aortic valve implantation (TAVI), post-procedure use of clopidogrel can be omitted to reduce bleeding without compromising antithrombotic efficacy, according to results from cohort B of the POPular TAVI trial presented at the American College of Cardiology and World Congress of Cardiology virtual meeting (ACC.20/WCC).
Obesity does not appear to be strongly correlated with an increased risk for febrile neutropaenia during levofloxacin prophylaxis in patients with haematological malignancies receiving intermediate-risk myelosuppressive chemotherapy, suggests a study.
Initiation or switch to the single-tablet regimen of bictegravir/emtricitabine/tenofovir alafenamide (TAF) led to low HIV-1 RNA viral load in people living with HIV (PLHIV), according to the BICSTaR study presented at HIV Glasgow 2020.
Use of corticosteroids appears to be an effective treatment for paediatric drug reaction with eosinophilia and systemic symptoms (DRESS), suggest the results of a recent study. In severe cases, corticosteroids used in conjunction with intravenous immunoglobulin result in fast clinical improvement.