Treatment with the PCSK9* inhibitor alirocumab led to clinically meaningful reductions in low-density lipoprotein cholesterol (LDL-C) among adults with homozygous familial hypercholesterolaemia (HoFH), according to data from the ODYSSEY-HoFH** trial presented at the ACC.20/WCC Virtual meeting.
Individuals who reported a normal sleeping duration of 6–8 hours a night showed a lower chance of developing heart disease or stroke than those who slept for either shorter or longer durations, according to a secondary analysis of the Corinthia study presented at the ACC.20/WCC Virtual Meeting.
A substudy of the REDUCE-IT* trial – REDUCE-IT EPA** – presented at the ACC.20/WCC Virtual Meeting shows that the level of eicosapentaenoic acid (EPA) in the blood achieved from the consumption of icosapent ethyl (IE) – a pure, stable EPA ethyl ester – propelled the substantial reductions in cardiovascular (CV) event rates in statin-treated patients.
The use of nicotine e-cigarettes (ECs) along with counselling is more efficacious in aiding smoking cessation than counselling alone, according to 12-week results of a multicentre, randomized study presented at the American College of Cardiology 2020/World Congress of Cardiology (ACC.20/WCC) virtual meeting.
Rivaroxaban plus aspirin is effective in lowering the incidence of major adverse limb and cardiovascular (CV) events in patients with peripheral artery disease (PAD) undergoing lower-extremity revascularization, according to results of the VOYAGER-PAD trial presented at the American College of Cardiology and World Congress of Cardiology 2020 virtual meeting (ACC.20/WCC).
Vericiguat significantly reduces cardiovascular (CV) deaths and heart failure (HF)-related hospitalizations in patients with high-risk HF, according to results of the VICTORIA trial presented at the American College of Cardiology and World Congress of Cardiology virtual meeting (ACC.20/WCC).
A higher number of daily steps appears to be associated with lower home blood pressure (BP) in middle-aged individuals, according to the electronic Framingham Heart Study (eFHS) presented at the ACC.20/WCC Virtual Meeting.
Evinacumab, a fully human monoclonal antibody inhibitor of ANGPTL3, effectively lowers LDL-cholesterol (LDL-C) levels in patients with homozygous familial hypercholesterolaemia (HoFH) regardless of their LDL receptor (LDLR) function, according to results of a double-blind phase III trial presented at the American College of Cardiology and World Congress of Cardiology virtual meeting (ACC.20/WCC).
MitraClip NTR and XTR systems are effective and well tolerated for primary mitral regurgitation (MR), as shown in the prospective, multicentre, single-arm, international, post-marketing, real-world, observational EXPAND study presented at the American College of Cardiology 2020/World Congress of Cardiology (ACC.20/WCC) virtual meeting.
Obesity does not appear to be strongly correlated with an increased risk for febrile neutropaenia during levofloxacin prophylaxis in patients with haematological malignancies receiving intermediate-risk myelosuppressive chemotherapy, suggests a study.
Initiation or switch to the single-tablet regimen of bictegravir/emtricitabine/tenofovir alafenamide (TAF) led to low HIV-1 RNA viral load in people living with HIV (PLHIV), according to the BICSTaR study presented at HIV Glasgow 2020.
Use of corticosteroids appears to be an effective treatment for paediatric drug reaction with eosinophilia and systemic symptoms (DRESS), suggest the results of a recent study. In severe cases, corticosteroids used in conjunction with intravenous immunoglobulin result in fast clinical improvement.