Type 2 diabetes mellitus patients treated with either the sodium-glucose cotransporter-2 inhibitor empagliflozin or dipeptidyl peptidase 4 inhibitors incur similar overall healthcare costs, according to data from the EMPRISE trial presented at the 79th Scientific Sessions of the American Diabetes Association (ADA 2019).
Supplementation with vitamin D among vitamin D-sufficient adults who are at high risk of developing diabetes does not reduce the risk of developing the disease vs placebo, according to the randomized, placebo-controlled D2d* trial.
Once-weekly subcutaneous injections of dulaglutide in patients with type 2 diabetes (T2D) reduced cardiovascular (CV) events, particularly non-fatal stroke, regardless of their CV history in the longest cardiovascular outcomes trial (CVOT) to date for a GLP-1* receptor agonist, REWIND**. The CV benefits come with potential renal benefits, with the largest effect seen for macroalbuminuria in an exploratory analysis.
Obesity does not appear to be strongly correlated with an increased risk for febrile neutropaenia during levofloxacin prophylaxis in patients with haematological malignancies receiving intermediate-risk myelosuppressive chemotherapy, suggests a study.
Initiation or switch to the single-tablet regimen of bictegravir/emtricitabine/tenofovir alafenamide (TAF) led to low HIV-1 RNA viral load in people living with HIV (PLHIV), according to the BICSTaR study presented at HIV Glasgow 2020.
Use of corticosteroids appears to be an effective treatment for paediatric drug reaction with eosinophilia and systemic symptoms (DRESS), suggest the results of a recent study. In severe cases, corticosteroids used in conjunction with intravenous immunoglobulin result in fast clinical improvement.