77th Scientific Sessions of the American Diabetes Association (ADA) 2017

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77th Scientific Sessions of the American Diabetes Association (ADA) 2017

09 June 2017 - 13 June 2017

ODYSSEY trials reveal positive effect of alirocumab on lipid profile in patients with T2D

Roshini Claire Anthony, 20170630140300

The PCSK9* inhibitor alirocumab reduced low-density lipoprotein cholesterol (LDL-C) levels and several other lipid parameters in patients with type 2 diabetes (T2D) and high cardiovascular risk, according to two studies presented at the 77^th Scientific Sessions of the American Diabetes Association (ADA 2017) held in San Diego, California, US.

Two-way text messaging may help glycaemic control in teens with T1D

Elaine Soliven, 20170630101003

More frequent text messaging responses to reminders to check blood glucose (BG) was associated with better glycaemic control in teens with type 1 diabetes (T1D), and may help the transition from paediatric to adult care which entails greater self-care routine, suggests a study presented at the American Diabetes Association’s 77^th Scientific Sessions held in San Diego, California, US.

Glucagon-blocking drug reduces need for insulin, improves blood glucose levels in T1D patients

Audrey Abella, 20170622083649

A single dose of the human glucagon receptor (GCGR) antibody, REMD-477, reduces the amount of insulin necessary and significantly improves glycaemic control in individuals with type 1 diabetes (T1D), according to a study presented at the ADA 2017 in San Diego, California, US.

Severe obesity linked to higher diabetes risk in children, adolescents

Elaine Soliven, 20170622063616

Severe obesity in children and adolescents may increase the risk of developing youth-onset diabetes, according to a study presented at the American Diabetes Association’s 77^th Scientific Sessions held in San Diego, California, US.

Comparable CV safety, reduced severe hypoglycaemia risk with insulin degludec vs insulin glargine

Roshini Claire Anthony, 20170621140200

Insulin degludec had comparable cardiovascular safety and reduced the risk of severe hypoglycaemia compared with insulin glargine U100 in patients with type 2 diabetes and high cardiovascular risk, according to results of the DEVOTE* study.

Podcast: Dr Steven Marso speaks about the cardiovascular safety of insulin degludec vs insulin glargine in patients with type 2 diabetes with high cardiovascular risk.

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Podcast: Dr Steven Marso speaks about the cardiovascular safety of insulin degludec vs insulin glargine in patients with type 2 diabetes with high cardiovascular risk.

Podcast: Professor Robert Henry talks about the effects of alirocumab vs usual care in patients with type 2 diabetes and mixed dyslipidemia.

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Podcast: Professor Robert Henry talks about the effects of alirocumab vs usual care in patients with type 2 diabetes and mixed dyslipidemia.

Podcast: Professor Bruce Neal summarizes the key findings of the Canagliflozin Cardiovascular Assessment Study.

20170621122245

Podcast: Professor Bruce Neal summarizes the key findings of the Canagliflozin Cardiovascular Assessment Study.

Podcast: Dr Carla Greenbaum speaks about the potential clinical impact of identifying individuals at risk of type 1 diabetes.

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Podcast: Dr Carla Greenbaum speaks about the potential clinical impact of identifying individuals at risk of type 1 diabetes.

Fasting plasma glucose predicts dietary weight loss success

Fasting glucose as biomarker for weight loss success?

Pearl Toh, 20170621100001

Individuals with high fasting plasma glucose (FPG) lost more weight than those who had low FPG in response to a high-fibre, low glycaemic load diet, suggesting that FPG could be used as a biomarker to predict dietary weight loss success and to guide selection of the most effective diet, in particular for those with prediabetes and diabetes, according to studies presented at ADA 2017.

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Eluxadoline offers symptom relief from IBS with diarrhoea

Pearl Toh, 18 Feb 2016

Treatment with eluxadoline, a new oral medication, relieved two major symptoms of irritable bowel syndrome with diarrhoea (IBS-D) — abdominal pain and diarrhoea, according to a study based on two phase III randomized controlled trials. [N Engl J Med 2016;374:242-253]

Oral antibiotics up risk of kidney stones

Tristan Manalac, 19 May 2018

Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.

CVD-REAL 2 demonstrates CV benefits of SGLT-2 inhibitors in Asia-Pacific, Middle East populations

Roshini Claire Anthony, 20 Mar 2018

Individuals with type 2 diabetes (T2D) who initiate therapy with sodium glucose cotransporter-2 (SGLT-2) inhibitors have lower risks of all-cause death and cardiovascular (CV) outcomes, specifically myocardial infarction (MI) and stroke, compared with those who initiate other glucose-lowering therapies, according to results from the CVD-REAL* 2 study.