Older age, presence of multiple comorbidities, and longer length of hospital stay, rather than difference in glycaemic control, were associated with an increased risk of 1-year death following admission with severe hypoglycaemia in patients with diabetes, according to a Singapore study.
Adding continuous glucose monitoring (CGM) to conventional finger-prick test during pregnancy increases the time spent in the recommended glycaemic target range and improves neonatal health outcomes in patients with type 1 diabetes (T1D) compared with traditional test alone, according to the CONCEPTT* study presented at EASD 2017.
Dapagliflozin improves glycaemic control with sustained weight loss without an increased risk of diabetic ketoacidosis (DKA) in patients with type 1 diabetes (T1D) who are inadequately controlled with insulin, according to the DEPICT-1* study.
Once-weekly doses of the glucagon-like peptide-1 receptor agonist exenatide plus insulin glargine improved glucose control and weight loss in patients whose type 2 diabetes (T2D) was uncontrolled on basal insulin and metformin, according to findings from the DURATION-7* trial.
The novel, G-protein coupled receptor 119 (GPR119) agonist DS-8500a demonstrated dose-dependent glucose-lowering effects and favourable improvements in lipid parameters that extended up to 12 weeks in Japanese patients with type 2 diabetes mellitus (T2D), according to data presented at EASD 2017.
Individuals with type 2 diabetes (T2D) who were hospitalized with nonalcoholic fatty liver disease (NAFLD) had an elevated risk of cardiovascular disease (CVD), and death due to CVD, hepatocellular cancer, and other causes, according to a study presented at EASD 2017.
The incidence of cardiovascular (CV) events at 5 years was similar when adding sulphonylureas or pioglitazone to metformin in patients with type 2 diabetes (T2D) inadequately controlled with metformin alone, according to a head-to-head comparison in the TOSCA.IT* trial.
A recent study conducted by The University of Hong Kong (HKU) revealed that long-term use of proton pump inhibitors (PPIs) is associated with a significantly increased risk of gastric cancer even in patients who have had Helicobacter pylori eradicated.
Pearl Toh spoke with Dr Teh Ming Ming, senior consultant at the Department of Endocrinology, Singapore General Hospital (SGH), on the major challenges of diagnosing and managing diabetes in primary care, in conjunction with the World Diabetes Day on 14 November. Awareness of the symptoms of diabetes is important, and patients should be empowered to manage their conditions.
New drug applications approved by US FDA as of 1 - 15 June 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.