Inhibition of the Notch signaling pathway by DAPT prevents proliferation and migration of ductus arteriosus smooth muscle cells (DASMCs) following induction by angiotensin-II (Ang-II), a new study presented at the recently concluded 21st Asian Pacific Society of Cardiology Congress (APSC 2017) has shown.
The use of sodium-glucose co-transporter 2 (SGLT2) inhibitors such as empagliflozin and canagliflozin may lead to a decreased risk of heart failure (HF), according to data presented at the Asian Pacific Society of Cardiology Congress (APSC) 2017 held in Singapore.
East Asians with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI) have lower incidence of thrombotic events but higher risk of bleeding compared with their Western counterparts in response to antiplatelet therapy, necessitating the need for guidance on antiplatelet treatment strategies specific for East Asian patients.
Alirocumab has a positive effect on low-density lipoprotein cholesterol (LDL-C) levels and appears to be well tolerated in patients with hypercholesterolemia and high cardiovascular risk, according to a sub-analysis of Taiwanese patients enrolled in the ODYSSEY KT* clinical trial.
There is significant heterogeneity among Asian patients with heart failure, with patients from Southeast Asia appearing to have the highest risk factor burden, according to findings of the ASIAN-HF* registry study presented at the 21st Asian Pacific Society of Cardiology Congress (APSC 2017) held in Singapore.
Transcatheter aortic valve replacement (TAVR) is the standard of care for high-risk patients with severe aortic stenosis (AS), and may be superior to open surgery in patients with lower risk as newer generation devices emerge, according to a presentation at the APSC Congress 2017 in Singapore.
Increasing the dose of loop diuretic at hospital discharge of patients with heart failure (HF) was not associated with a reduced risk of hospital readmission for HF or any cause contrary to previous reports suggesting that such a dosing strategy could reduce readmission, according to a study presented at the 21st Asian Pacific Society of Cardiology Congress (APSC 2017) in Singapore.
Nonvitamin K antagonist oral anticoagulants (NOAC)-associated intracerebral haemorrhage (ICH) and vitamin K antagonists-ICH appear to have similar ICH volume, haematoma expansion, functional outcome and mortality, results of a recent meta-analysis have shown.