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Local anaesthesia prior to open dacryocystorhinostomy during TIVA eases postoperative pain, recovery

15 hours ago

A recent study has shown that ipsilateral infiltration of local anaesthesia (LA) containing epinephrine in the paranasal tissues prior to external dacryocystorhinostomy under total intravenous general anaesthesia (TIVA) results in a 28-percent decrease in mean propofol usage and a 61-percent reduction in remifentanil usage.

Statins do not prevent CV events, mortality in old patients without T2D

Stephen Padilla, 16 hours ago

Statin treatment does not appear to reduce atherosclerotic cardiovascular disease (CVD) or all-cause mortality in patients without type 2 diabetes (T2D) aged ≥75 years, even when the incidence of atherosclerotic CVD is significantly higher than the risk thresholds proposed for statin use, according to a recent study.

5α-reductase inhibitors improve bladder cancer survival

Yesterday

Treatment with 5α-reductase inhibitors improves disease-specific survival following a diagnosis of bladder cancer, suggests a recent study. On the other hand, α-blockers do not appear to improve bladder cancer survival.

Heat-stable carbetocin noninferior to oxytocin in preventing post-partum haemorrhage

Elaine Soliven, 2 days ago

Intramuscular administration of heat-stable carbetocin was noninferior to oxytocin in preventing post-partum blood loss among women who underwent a vaginal delivery, according to the CHAMPION* trial.

Infliximab plus IVIG better than IVIG alone as initial therapy in KD patients with coronary artery lesions

2 days ago

Initial treatment with intravenous immunoglobulin (IVIG) plus infliximab lessens the need for additional therapy in Kawasaki disease (KD) patients presenting with coronary artery lesions (CALs), a recent study has shown.

Adding sildenafil to nintedanib shows no benefit in idiopathic pulmonary fibrosis

Jackey Suen, 3 days ago

The addition of sildenafil to nintedanib provides no improvements in health-related quality of life (HRQoL) in patients with idiopathic pulmonary fibrosis (IPF), according to results of the INSTAGE study presented at the 28th European Respiratory Society International Congress 2018 (ERS 2018).

Many high-risk Asians inadequately treated for high LDL-C

Pearl Toh, 3 days ago

Low-density lipoprotein cholesterol (LDL-C) levels remained high in many patients with stable or acute coronary heart disease (CHD) in Asia, despite having a very high risk of recurrent cardiovascular (CV) events, indicating that the use of lipid-lowering therapies and lipid monitoring were inadequate.

Optimizing hypertension management in clinical practice with nebivolol

Prof. Giuseppe Mancia, Prof. Jong-Won Ha, Prof. Lin Jiunn-Lee, 11 Jul 2018

Hypertension guidelines diﬀer in their recommendation to use beta-blockers as ﬁrst-line agents. At a Menarini-sponsored symposium held during the Asian Paciﬁc Society of Cardiology Congress 2018 in Taipei, Taiwan, Professor Giuseppe Mancia from the University of Milano-Bicocca in Milan, Italy and Professor Jong-Won Ha from the Yonsei University College of Medicine in Seoul, Korea discussed the rationale behind these recommendations, and reviewed the role of beta-blockers in hypertension management, particularly the role of vasodilatory beta-blocker nebivolol (Nebilet^®, Menarini). Professor Lin Jiunn-Lee, APSC 2018 chairman and president of the Taiwan Society of Cardiology, chaired the symposium.

Improving Medical Practice through Advancement in Clinical Treatment: IMPACT Aesthetics & Suturing Workshop 2018

Dr. Steven Ang, Dr. Leo Kah Woon, 11 Jul 2018

DCH Auriga recently held their first Aesthetics and Suturing Workshop under the IMPACT continuing medical education series – a scientific platform that aims to cascade the latest updates on disease management and share best clinical practices among healthcare professionals in Singapore. Two experts on aesthetics and aesthetic surgery shared their insights on suturing techniques and current approaches for scar prevention and management.

Excerpts from the expert meeting on the use of topical NSAIDs in musculoskeletal pain

01 Jul 2018

With the objective of establishing a Malaysian consensus on the use of topical NSAIDs in the management of musculoskeletal pain, this meeting brought together experts from various backgrounds, ie, rheumatology, pharmacy, orthopaedics and general medicine. At the meeting, Dr Mary Suma Cardosa delivered a talk on the pathophysiology and effective management of pain, while the lecture by Dr Yeap Swan Sim focused on the management of musculoskeletal and soft-tissue pain. This article presents excerpts from the expert meeting and features the consensus statements agreed during the meeting.

Legacy of BP, lipid lowering: Long-term survival benefit

Pearl Toh, 20 Sep 2018

The survival benefits conferred by blood pressure (BP) and lipid-lowering medications persist even after more than a decade following the end of the original trial, according to results from the ASCOT* Legacy study.

Factor Xa inhibitor failed in reducing mortality among heart failure patients without AF

Dr. Joseph Delano Fule Robles, 30 Aug 2018

The factor Xa inhibitor rivaroxaban failed in reducing the risk of death, MI or stroke as compared with placebo among patients with worsening chronic heart failure (HF) and underlying coronary artery disease (CAD) without atrial fibrillation (AF), according to results of the COMMANDER HF trial reported at the European Society of Cardiology (ESC) Congress 2018.

CAMELLIA–TIMI 61: Lorcaserin first weight-loss agent to show CV safety in high-risk patients

Jackey Suen, 30 Aug 2018

Lorcaserin has become the first weight-loss agent to show cardiovascular (CV) safety in patients at high CV risk, according to results of the CAMELLIA–TIMI 61 study presented at the European Society of Cardiology (ESC) Congress 2018.

Younger lymphoma patients may be less susceptible to chemo-induced ovarian toxicity

Pearl Toh, 27 Aug 2018

Chemotherapy may be less damaging to fertility of female lymphoma patients who are of a younger age than those who are older, even in the case of an alkylating regimen, suggests a study presented at ESHRE 2018.

No harms on offspring cognition with peripartum ART

Pearl Toh, 21 Aug 2018

Use of triple antiretroviral therapy (ART) during pregnancy and breastfeeding did not affect the cognitive development and function of the offspring compared with those whose mothers were not exposed to ART, reveals the IMPAACT PROMISE-BF study presented at the IAC 2018.

Dual therapy comparable with triple therapy for initial HIV-1 treatment

Roshini Claire Anthony, 18 Aug 2018

The combination of dolutegravir + lamivudine appeared noninferior to dolutegravir + tenofovir/emtricitabine in reducing viral load in treatment-naïve patients with HIV-1 infection, according to the phase III GEMINI-1 and GEMINI-2* trials presented at AIDS 2018.

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