Top Medical News
3 hours ago
New drug applications approved by US FDA as of 01 - 15 November 2018 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Tristan Manalac, 17 hours ago
Frailty does not impair the efficacy of influenza vaccination in elderly adults, according to a recent Singapore study, which showed that similar degrees of seroprotection and vaccination-induced humoral immune responses were achieved across the different categories of frailty.
Yesterday
Daily aspirin use appears to significantly improve survival outcomes following radical cystectomy, a recent study has found.
Yesterday
Among psoriasis patients new to systemic medication, adherence to biologics is better than to methotrexate, reports a recent study.
Pearl Toh, 2 days ago
Zoledronate significantly reduces the risk of both nonvertebral and vertebral fragility fractures over 6 years in older women with osteopenia — a substantial patient group at risk for fractures but in whom a knowledge gap remains for pharmacological treatment, reveals a large randomized trial.
Roshini Claire Anthony, 2 days ago

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Dr. Erik Fung, Dr. Kevin KH Kam, 3 days ago
In this case report, we present the challenges encountered by physicians and cardiologists managing patients with advanced HF, and highlight the broadening spectrum of medical therapies and pathways that comprise contemporary practice.
Special Reports
01 Nov 2018
The prevalence of allergic diseases in the Asia-Pacific region is expected to rise over the next 20 years, driven by rapid economic development and urbanization. Allergic diseases have high socioeconomic impact by impairing productivity and quality of life, and the impact may be greater in Asia-Pacific than in Europe due to the presence and predominance of perennial allergens.
Dr. Robert Giugliano, Prof. Ulrich Laufs, Prof. Gaetano De Ferrari, Prof. Naveed Sattar, 11 Oct 2018

The FOURIER trial previously demonstrated that adding the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor evolocumab to background statin therapy lowered LDL-cholesterol (LDL-C) below target levels and significantly reduced the risks of cardiovascular (CV) events in patients with atherosclerotic cardiovascular disease (ASCVD). At the European Society of Cardiology (ESC) Congress 2018 in Munich, Germany, experts reiterated how evolocumab helps lower LDL-C levels and reduces CV events even in patients with various comorbidities.

27 Sep 2018
PRALUENT – alirocumab 75 mg/mL and 150 mg/mL soln for inj - sanofi-aventis
27 Sep 2018
VICTOZA – Liraglutide 6 mg/mL soln for inj - Novo Nordisk
27 Sep 2018
SKYCELLFLU – Inactivated quadrivalent influenza vaccine (inj) 0.5 mL - AJ Biologics
Rachel Soon, 01 Sep 2018

MIMS Pharmacist presents an overview of a standardized extract of Pinus pinaster bark, and its potential role in slowing down the progression of diabetic retinopathy.

Rachel Soon, 25 Jul 2018

MIMS Pharmacist presents an overview of Lactobacillus plantarum 299v's physiological role, as well as contemporary research on its pharmacology and effects.

Conference Reports
Elvira Manzano, 11 Nov 2018
Low-dose methotrexate, which is approved for the treatment of rheumatoid arthritis (RA) and other autoimmune disorders, has shown unexpectedly disappointing results in preventing cardiovascular (CV) events among patients with a prior myocardial infarction (MI) or multivessel coronary disease, according to CIRT*, potentially ruling out what could be an affordable option for treating inflammation related to atherosclerosis.
Roshini Claire Anthony, 09 Nov 2018

Patients with advanced, unresectable melanoma may derive overall survival (OS) and progression-free survival (PFS) benefits when treated with a nivolumab plus ipilimumab combination or nivolumab alone, according to 4-year results of the phase III CheckMate 067* trial presented at ESMO 2018.

Audrey Abella, 09 Nov 2018
The drug combination comprising gemcitabine, cisplatin, and S-1 (GCS) led to significant survival benefits compared with the standard dual chemotherapy regimen of gemcitabine and cisplatin (GC) among patients with advanced biliary tract* cancer (BTC), according to results of the KHB01401–MITSUBA** trial presented at ESMO 2018.
Pearl Toh, 05 Nov 2018
Taking a high daily dose multi-strain probiotic may help reduce incidence of mild-to-moderate chemotherapy-induced diarrhoea (CID), a side effect commonly experienced by cancer patients, suggests a randomized study presented at ESMO 2018.
Pearl Toh, 02 Nov 2018
Combining the anti-PD-L1 avelumab with the VEGFR* blocker axitinib significantly improves progression-free survival (PFS) compared with sunitinib as first-line therapy for advanced renal cell carcinoma (RCC), according to the JAVELIN Renal 101** trial.
Pearl Toh, 01 Nov 2018
Treatment with the PD-L1 inhibitor atezolizumab on top of standard chemotherapy with nab-paclitaxel significantly improves progression-free survival (PFS) in triple-negative breast cancer (TNBC) compared with nab-paclitaxel alone, top-line results from the IMpassion* 130 trial reveal. In particular, median overall survival (OS) was 10 months longer with atezolizumab among PD-L1-positive (PD-L1+) patients in an interim analysis.
Roshini Claire Anthony, 01 Nov 2018

Patients with previously treated metastatic gastric adenocarcinoma had improved overall survival (OS) when a trifluridine-tipiracil combination was added to a supportive care regimen compared with best supportive care alone, according to findings of the phase III TAGS* trial.

CME Modules
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