Parkinson's disease is a progressive neurodegenerative disorder that is common, age-related and chronic.
It is caused by loss or degeneration of dopaminergic neurons in the substantia nigra of the midbrain.
Onset of symptoms and progression of the disease is gradual.
Motor signs and symptoms include resting tremor, rigidity, bradykinesia and postural instability.
Parkinson's disease dementia indicates loss of intellectual functions
including memory, significant deterioration in the ability to carry out
day-to-day activities and changes in social behavior are often noted.
Prompt treatment with tranexamic acid may reduce intracerebral haemorrhage (ICH) growth in patients with ongoing bleeding, though the timing of treatment appears to be key to improved outcomes, according to a study presented at ISC 2020.