Parkinson's disease is a progressive neurodegenerative disorder that is common, age-related and chronic.
It is caused by loss or degeneration of dopaminergic neurons in the substantia nigra of the midbrain.
Onset of symptoms and progression of the disease is gradual.
Motor signs and symptoms include resting tremor, rigidity, bradykinesia and postural instability.
Parkinson's disease dementia indicates loss of intellectual functions
including memory, significant deterioration in the ability to carry out
day-to-day activities and changes in social behavior are often noted.
Monthly injections of the PCSK9* monoclonal antibody evolocumab effectively reduced plasma LDL-cholesterol (LDL-C), often referred to as the bad cholesterol, in teenagers with heterozygous familial hypercholesterolaemia (HeFH) already taking statins, with or without ezetimibe, the HAUSER-RCT has shown.
For individuals with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.