pancreatitis%20-%20chronic
PANCREATITIS - CHRONIC
Chronic pancreatitis develops from irreversible scarring sustained by the pancreas from prolonged inflammation.
Signs and symptoms include abdominal pain that is epigastric in location that radiates to the back and frequently occurs at night or after meals, symptoms of fat, protein & carbohydrates maldigestion that become apparent with advanced chronic pancreatitis and presence of diarrhea.
Chronic pancreatitis results in destruction of alpha and beta cells which gives rise to deficiencies of both insulin and glucagon.

Pancreatitis - Chronic References

  1. Warshaw AL, Banks PA, Fernández-Del Castillo C. AGA technical review: treatment of pain in chronic pancreatitis. Gastroenterology. 1998 Sep;115(3):765-776. PMID: 9721175
  2. American Gastroenterological Association. American Gastroenterological Association medical position statement: treatment of pain in chronic pancreatitis. Gastroenterology. 1998 Sep;115(3):763-764. PMID: 9721174
  3. Etemad B, Whitcomb DC. Chronic pancreatitis: diagnosis classification, and new genetic developments. Gastroenterology. 2001 Feb;120(3):682-707. PMID: 11179244
  4. Feldman M, Friedman LS, Sleisenger MH, eds. Sleisenger and Fordtran’s gastrointestinal and liver disease: pathophysiology/diagnosis/management. 7th ed. Pennsylvania: Saunders; 2002
  5. MedWormhttp://www.medworm.com/rss/index.php/Gastroenterology/17/http://www.medworm.com/rss/medicalfeeds/specialities/Gastroenterology.xml
  6. MedWormhttp://www.medworm.com/rss/index.php/Pediatrics/33/http://www.medworm.com/rss/medicalfeeds/specialities/Pediatrics.xml
  7. The Society for Surgery of the Alimentary Tract. SSAT patient care guidelines: operative treatment for chronic pancreatitis. http://www.ssat.com. May 2004. Accessed 15 Aug 2005.
  8. Banks PA, Conwell DL, Toskes PP. The management of acute and chronic pancreatitis. Gastroenterol Hepatol (NY). 2010 Feb;6(Suppl 2 Suppl 3):1-16. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886461/pdf/GH-06-S5-1.pdf. Accessed 05 Mar 2014. PMID: 20567557
  9. Freedman SD. Treatment of chronic pancreatitis. UpToDate. http://www.uptodate.com. 08 Oct 2013. Accessed 05 Mar 2014.
  10. Forsmark CE. Pancreatitis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016. 963-967. :963-967.
  11. Arvanitakis M, Ockenga J, Bezmarevic M, et al. ESPEN guideline on clinical nutrition in acute and chronic pancreatitis. Clin Nutr. 2020 Mar;39(3):612-631. doi: 10.1016/j.clnu.2020.01.004. Accessed 09 Nov 2020. PMID: 32008871
  12. Chauhan SS, Pannu DS, Forsmark CE. Antioxidants as adjunctive therapy for pain in chronic pancreatitis. Practical Gastroenterology. 2012;36(3):42–49. doi: https://med.virginia.edu.
  13. Gardner TB, Adler DG, Forsmark CE, et al. ACG clinical guideline: chronic pancreatitis. Am J Gastroenterol. 2020 Mar;115(3):322-339. doi: 10.14309/ajg.0000000000000535. PMID: 32022720
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