pancreatitis%20-%20chronic
PANCREATITIS - CHRONIC
Chronic pancreatitis develops from irreversible scarring sustained by the pancreas from prolonged inflammation.
Signs and symptoms include abdominal pain that is epigastric in location that radiates to the back and frequently occurs at night or after meals, symptoms of fat, protein & carbohydrates maldigestion that become apparent with advanced chronic pancreatitis and presence of diarrhea.
Chronic pancreatitis results in destruction of alpha and beta cells which gives rise to deficiencies of both insulin and glucagon.

Lifestyle Modification

Abstinence from Alcohol & Tobacco

  • Patients should be encouraged to abstain from drinking alcohol & smoking
  • Mortality has been found to increase w/ continued smoking & abuse of alcohol
    • Alcohol abuse speeds up the development of pancreatic dysfunction
    • Smoking accelerates disease progression & may increase pancreatic cancer risk
  • Diminishing alcohol intake has been seen to result in decreased pain associated w/ chronic pancreatitis

Eating Small Meals & Keeping Hydrated

  • Low-fat small meals & adequate hydration may be helpful
  • Medium chain triglycerides (MCTs) improve pain by minimally increasing cholecystokinin (CCK) levels or through its antioxidant effect
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Gastroenterology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 2 days ago

A subgroup of patients with HBeAg-negative chronic hepatitis B virus (HBV) infection who ceased their long-term nucleotide analogue treatment maintained virological suppression, pointing to a group of patients who may be suitable for treatment cessation, according to a recent study.

Rachel Soon, 4 days ago

Gels utilizing Stichopus horrens (golden sea cucumber/gamat) extract show a similar efficacy to standard-of-care hydrogels for promoting wound healing, according to a prospective study.

3 days ago
Higher cancer symptom burden in elderly adults is associated with functional impairment, reports a recent study.
Yesterday
The monoclonal antibody abrilumab is effective for treating moderate-to-severe ulcerative colitis, promoting remission, clinical response and mucosal healing, a recent study has found.