panbronchiolitis%20-%20diffuse
PANBRONCHIOLITIS - DIFFUSE
Diffuse panbronchiolitis is an inflammatory disease affecting the respiratory bronchioles.
It causes progressive suppurative and obstructive respiratory disease.
This is an idiopathic disease which is primarily found in Japan, Korea and China.
Predisposition to the disease may be genetically-related but environmental factors should also be considered.
Failure to treat diffuse panbronchiolitis can lead to development of bronchiectasis, progressive failure and death.

Surgical Intervention

Invasive Exam

  • Eg bronchoscopy w/ lavage, surgical lung biopsy
  • Done to confirm the diagnosis if findings of the radiographic studies are non-specific
  • Bronchiolar inflammation w/ transmural infiltrates of lymphocytes, plasma cells, & foam cells are seen in lung biopsy
  • Fluid obtained via bronchoscopy often reveals increased lymphocytes & neutrophils
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Respirology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
26 Apr 2016
Varenicline increases the rate of smoking cessation in individuals who smoke less than 10 cigarettes/day (cpd) based on a randomised, placebo- controlled clinical trial.
19 Jul 2016
New therapies that specifically target inflammatory pathways or aberrant physiology in severe asthma offer substantial opportunities for effective treatment. Some of these therapies are available under specialist referral, and others are available in the context of clinical trials.
Jairia Dela Cruz, 22 Aug 2018
Fast food consumption appears to be detrimental to health, with hamburgers having been shown to have a dose-response association with the risk of asthma.
Audrey Abella, 13 Dec 2016
Even a small number of cigarettes per day (CPD) used in the long term increases mortality risk, according to a  US study, highlighting the importance of smoking cessation.