panbronchiolitis%20-%20diffuse
PANBRONCHIOLITIS - DIFFUSE
Diffuse panbronchiolitis is an inflammatory disease affecting the respiratory bronchioles.
It causes progressive suppurative and obstructive respiratory disease.
This is an idiopathic disease which is primarily found in Japan, Korea and China.
Predisposition to the disease may be genetically-related but environmental factors should also be considered.
Failure to treat diffuse panbronchiolitis can lead to development of bronchiectasis, progressive failure and death.

Panbronchiolitis%20-%20diffuse Management

Follow Up

  • Follow up & assess patient’s overall clinical response after 6 months of macrolide treatment
  • If patient shows good response w/ macrolide, eg pulmonary function, clinical, radiological findings have improved, complete the treatment for 2 years
  • If symptoms recur after stopping the treatment, resume medication
  • In patients w/ respiratory failure & extensive bronchiectasis, continue treatment for >2 years
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