Frailty is associated with greater treatment cost and mortality among hospitalized children with cancer, suggests a US study, noting the need for further research on frailty-based risk stratification, as well as individualized intervention to improve patient outcomes.
Treating postnatal depression with selective serotonin reuptake inhibitors (SSRIs) may be beneficial for both mothers and their children in the long term, with a recent study showing that SSRIs can reduce the risk of several negative outcomes, such as maternal depression and child behavioural problems, according to a study.
New drug applications approved by US FDA as of 16-31 August 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Retinopathy of prematurity (ROP) appears to be the leading cause of childhood blindness, reveals a recent study in the US. More than half of these blind patients have had a treatable cause of blindness.
Uptake of COVID-19 vaccine among children 12–17 years of age is high (~80 percent) in Singapore, but for the 5–11-year age group, it is less than 30 percent. This could have been driven in part by vaccine hesitancy among parents. [Front Pediatr 2022;10:994675]
Despite the striking mortality burden of respiratory syncytial virus (RSV), no active vaccines are currently available to prevent RSV in children, says Dr Sherlock Lai, medical director, Moderna Singapore, at SiPPAC 2023.
The administration of soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) in very preterm (VPI; <32 weeks) and very low birthweight infants (VLBWI; <1,500 g) helps lower peak levels of plasma total bilirubin (TB), direct bilirubin (DB), alkaline phosphatase (ALP), and triglycerides (TG) during hospitalization, as shown in a recent study.