Having supportive family relationships may help youth maintain good asthma management behaviours despite difficult neighbourhood conditions--thus serving as a buffer against poor asthma outcomes associated with living in disorderly neighbourhoods, a recent study finds.
Children who were born after frozen embryo transfer (FET) showed comparable growth outcomes during their first 5 years of life as those who were born after fresh ET, according to a study presented at ESHRE 2019.
Treatment with voxelotor, an HbS* polymerization inhibitor, significantly increases haemoglobin (Hb) levels and reduces markers of haemolysis, including indirect bilirubin level and percentage of reticulocytes, compared with placebo in patients with sickle cell disease, according to the HOPE** trial.
Exposure to acid suppression therapy, such as proton pump inhibitors, within the first year of life appears to pose an increased fracture risk in children, with the risk amplified by days of use and earlier initiation, a study has found.
Children with noncritical infections and no gastrointestinal symptoms show similar gut and innate immune cell alterations as those with severe sepsis or organ failure, according to a study. Such changes are associated with increased morbidity and mortality and with a higher risk of future infections.
Teens with severe obesity need not wait until they are adults to undergo Roux-en-Y gastric bypass, with 5-year follow-up data from a recent study showing that the bariatric procedure leads to substantial weight loss that is similar in magnitude in adolescents and adults.
A 2-week course of the immunotherapy drug teplizumab delayed the onset of type 1 diabetes (T1D) in individuals at high risk for the condition, according to a phase II trial conducted by the TrialNet Study Group and presented at ADA 2019.
Baseline body mass index (BMI) and, to a lesser extent, school socioeconomic status are associated with subsequent weight status in schoolchildren, according to a study. Lifestyle behaviours show a lower effect as compared with prior BMI, but children with a healthier lifestyle have a reduced risk of overweight and obesity at follow-up.
Use of electronic vapour products (EVP), or vaping, has been associated with an increased likelihood of engaging in sexual and substance-use risk behaviours among US teenagers, according to data from the 2017 National Youth Risk Behaviour Survey presented at the Paediatric Academic Societies (PAS) 2019 Meeting.
Parenteral antibiotic therapy duration for bacteraemic urinary tract infection (UTI) in young infants may be safely shortened, according to a recent study showing that recurrence and readmission or emergency department revisitation rates are comparable between a ≤7-day and a longer therapy course.