Oral H1-antihistamines are the initial treatment of choice for allergic rhinitis (AR) and chronic urticaria in the primary care setting. However, in a diverse population of patients with AR and urticaria, primary care physicians are faced with the challenge of prescribing the best therapy amid a wide armamentarium of antihistamines available.
Complication rates related to the use of umbilical venous catheters (UVCs) in Singapore are comparable to international norms, but UVCs may lead to serious complications and must be used with caution in neonates, according to a study.
Parenting by lying – defined as lying that “aims to elicit children’s compliance” – may have negative psychosocial outcomes in children that can persist into adulthood, according to a study from Singapore.
A multicentre, double-blind, placebo-controlled, phase III randomized clinical trial (RCT) has found add-on fenfluramine to significantly reduce monthly convulsive seizure frequency in patients with Dravet syndrome (DS) whose condition was insufficiently controlled with stiripentol-containing antiepileptic drug (AED) regimens.
Dr. Kubi Appiah, Dr. Piya Chaemsaithong, Dr. Liona Chiu Yee Poon, 20191129085839
Preterm birth (PTB) is birth that occurs before 37 weeks’ gestation, and it is a leading cause of perinatal morbidity and mortality.1 Babies born before 34 weeks’ gestation are particularly associated with high rates of morbidity and mortality.2 They are also at risk of long-term medical and social sequelae.3 It is therefore important to institute preventative measures that can help mitigate the occurrence of PTB in pregnant women.
Childhood cancer survivors who were treated with radiotherapy and anthracyclines may have an elevated risk of developing subsequent breast cancer, according to an analysis of patients in the North American Childhood Cancer Survivor Study.
Combining Renal Angina Index (RAI) and urinary Neutrophil Gelatinase Associated Lipocalin (uNGAL) tests may help clinicians to detect and predict the development of severe acute kidney injury (AKI) in children admitted to the PICU*, according to a study presented at ASN Kidney Week 2019.
Infants with low Apgar scores within the normal range (7–10) are at increased risks of neonatal mortality and morbidity, according to a study in Sweden. Compared with infants with stable Apgar scores of 10, those with a decrease in score from 5–10 minutes are also at higher risk of morbidity.
Maternal exposures to heavy metals vanadium (V), arsenic (As) and lead (Pb) at early pregnancy appear to result in lower maternal free T3 (FT3) and FT3/free T4 (FT4) ratio, which may contribute to reduced birthweight, suggests a recent study.