Despite a 90-percent cure rate after first treatment for children with acute lymphoblastic leukaemia (ALL), approximately 10–15 percent of patients with paediatric ALL will experience relapse. [Expert Rev Anticancer Ther 2017;17:725-736] A recent webinar on the current landscape of ALL highlighted the potential of immunotherapy for paediatric patients with relapsed or refractory ALL, thus providing hope for this high-risk patient group.
Neonates with symptomatic novel coronavirus disease (COVID-19) more frequently require respiratory support, with high C-reactive protein (CRP) levels or greater prothrombin time (PT) indicating a more severe disease, according to a recent study.
Adolescents who are aware of their friends’ self-injurious behaviours are at risk of the same tendencies and exhibit greater suicidality, according to a new study. Intervention efforts should also seek to target this peer influence effect in reducing suicidal behaviours among teens.
Antiviral treatment with tenofovir alafenamide fumarate (TAF) during pregnancy in highly viraemic mothers effectively prevents mother-to-child transmission (MTCT) of hepatitis B virus (HBV) with no safety concerns, according to two studies presented during the AASLD 2020 Liver Meeting.