New drug applications approved by US FDA as of 16-31 January 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
In preschool-aged children, higher digital media use (screen time) was associated with lower cortical thickness (CT) and sulcal depth (SD), according to a secondary analysis of data collated for an MRI-based study.
Childhood cancer survivors (CCS) appear to have an increased risk of low bone mineral density (BMD) and fracture compared with the general population, according to a cross-sectional study from the Netherlands.
Treatment with lebrikizumab, when combined with low- to mid-potency topical corticosteroid (TCS), helps reduce disease severity in adolescent and adult patients with moderate-to-severe atopic dermatitis (AD), with a safety profile consistent with that reported in previous AD studies, according to the phase III ADhere trial.
Teen and adult patients with drug-resistant epilepsy may benefit from modified Atkins diet, which has been shown in a recent study to produce improvements in seizure frequency, quality of life (QOL), and behavioural problems as compared with standard drug therapy.
Children with overweight or obesity appear to exhibit alterations in brain structure and function that can be detrimental to cognitive function and school performance, according to data from the Adolescent Brain Cognitive Development (ABCD) study.
Growing up on a farm appears to confer a reduced risk of developing allergic rhinitis in children, with the protective effect of farm living being set until school age and sustained through early adulthood.