After evaluating a retrospective case series of paediatric patients with atopic dermatitis (AD), researchers from the Chinese University of Hong Kong (CUHK) found thata positive bronchial challenge test (BCT) result is independently and positively associated with personal history of asthma and sibling history of atopy, but not with any other clinical parameters.
An evaluation of the cost-effectiveness of two rotavirus vaccines, carried out by researchers in Hong Kong, the UK and the US, shows that vaccination is likely to be cost-saving to the Hong Kong government and payers.
Treatment with the human monoclonal antibody tezepelumab reduced exacerbations and improved asthma control, lung function, and quality of life in adults and adolescents with severe, uncontrolled asthma, according to the phase III NAVIGATOR study presented as a poster at AAAAI 2021.
Long-term administration of vosoritide, a potent stimulator of endochondral bone growth, led to persistent and stable growth outcomes in children aged 5–18 years with achondroplasia, according to the ongoing phase III extension study results presented at ENDO 2021.
Dr Jeremy Lin, a consultant at the Division of Paediatric Neurology, Khoo Teck Puat – National University Children’s Medical Institute, National University Hospital, Singapore, provides Roshini Claire Anthony with an in-depth look on spina bifida and explains the crucial role played by the primary care physician in managing this condition.
The novel box-type device Endoshield can help prevent the spread of the novel coronavirus disease (COVID-19) during paediatric endoscopic procedures, according to a Thailand study. This protective barrier is affordable, usable, and is suitable for use both at the left lateral and supine positions.
Fast-track cardiac anaesthesia (FTCA) using a combination of remifentanil and dexmedetomidine is effective and safe for the transthoracic device closure of atrial septal defect (ASD) in children, according to a new study.
New drug applications approved by US FDA as of 16-31 March 2021 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
While early-phase clinical trials may demonstrate substantial levels of overall response rates in patients with relapsed/refractory multiple myeloma (RRMM), high heterogeneity of evidence prevents the accurate assessment of clinical benefit before patient participation, reports a recent meta-analysis.
The COVID-19 vaccine AZD1222 by AstraZeneca and the University of Oxford was 79 percent effective overall in preventing symptomatic infections – higher than observed in previous clinical trials of the vaccine – at the interim analysis of a US phase III trial.
Migraine and headache are common ailments of people living in the modern era. Dr Jon Marshall of The Singapore Headache and Migraine Clinic shares his insights with Pearl Toh on how to manage migraine and headache using non-pharmaceutical strategies, with a focus on the manual medicine approach.