Adolescents with disruptive behaviour disorder (DBD), with and without callous-unemotional (CU) traits, have reduced dorsal anterior cingulate cortex (ACC) activation during reward anticipation relative to typically developing youths, a study has shown.
Lubiprostone does not appear to have any favourable effect in the treatment of paediatric functional constipation (PFC), although the drug has a safety profile similar to that reported in adults, as shown in a phase III study.
The mean rate of change in plasma 25-hydroxyvitamin (25[OH]D) during pregnancy is predictive of birth weight z-scores and is associated with the risks for large for gestational age (LGA) and preterm birth, suggests a recent study.
Allergic rhinitis is highly prevalent among school children in Taiwan, a recent study has found. Antibiotic exposure and having a cat in the house during the first year of life appear to be important risk factors.
Among patients with hand, foot, and mouth disease (HFMD) released from quarantine, there remain high positive rates of viral shedding, but the duration is not consistent among HFMD patients caused by different serotypes, as indicated by the results of a recent study.
While early-phase clinical trials may demonstrate substantial levels of overall response rates in patients with relapsed/refractory multiple myeloma (RRMM), high heterogeneity of evidence prevents the accurate assessment of clinical benefit before patient participation, reports a recent meta-analysis.
The COVID-19 vaccine AZD1222 by AstraZeneca and the University of Oxford was 79 percent effective overall in preventing symptomatic infections – higher than observed in previous clinical trials of the vaccine – at the interim analysis of a US phase III trial.
Migraine and headache are common ailments of people living in the modern era. Dr Jon Marshall of The Singapore Headache and Migraine Clinic shares his insights with Pearl Toh on how to manage migraine and headache using non-pharmaceutical strategies, with a focus on the manual medicine approach.