Despite the absence of a substance use problem, regular cannabis use is associated with psychosocial impairment among adolescents and young adults, a study suggests. On the other hand, regular users with cannabis use disorder appear to exhibit high psychiatric comorbidity and more severe psychosocial impairment.
A conventional intervention promoting breastfeeding, healthy eating and physical activity in women during pregnancy has unexpectedly resulted in adverse long-term weight outcomes in their offspring, while a less conventional sleep intervention has maintained its positive outcomes at age 5 years, according to the results of a follow-up of the Prevention of Overweight in Infancy (POI) study.
Citrin-deficient children have increased high-density lipoprotein cholesterol (HDL-C) and sterol marker concentrations after neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD), according to a study. In addition, these children have significantly enhanced cholesterol synthesis and elimination in the liver and brain.
Infants born preterm are at heightened risk of developing sensory disabilities, such as hearing loss and visual impairment, a study has found. Other risk factors include intracranial haemorrhage and convulsions.
Ondansetron has been increasingly used for treating nausea and vomiting in pregnancy, and first-trimester exposure to the drug appears to pose no increased risk of birth defects, a study has found. However, there is a modest association found for cleft palate and renal agenesis–dysgenesis.
Early childhood exposure to lead appears to increase the risk of attention-deficit/hyperactivity disorder (ADHD), according to a recent study. Moreover, this effect is more pronounced for boys than for girls.
Thalassaemia becomes a global health problem. Most women with thalassaemia trait can be picked up by universal prenatal screening for thalassaemia using mean corpuscular volume/haemoglobin, followed by haemoglobin pattern with or without DNA analysis.