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Paediatrics
Top Medical News
Adolescents with chronic hepatitis C virus (HCV) infection are prone to develop significant fibrosis, including cirrhosis, reveals a study. Serum biomarkers aspartate transaminase-to-platelet ratio index (APRI) and Fibrosis-4 index (FIB-4) are positively associated with liver stiffness measurement (LSM).
Serum 25-hydroxyvitamin D (25[OH]D) at age 1 year shows an inverse association with childhood body mass index for age z score (BMIZ), percentage body fat at age 16/17 years, and a metabolic syndrome (MetS) score at age 16/17 years, a recent study has found.
Speech and language therapy, as supplemented with augmentative and alternative communication technology, allows children who are deaf or hard of hearing to process and comprehend spoken language more fully, as shown in a study.
Functional Family Therapy (FFT) is an effective holistic rehabilitation intervention even in non-Western cultures, leading to better probation completion rates, family functioning, and mental well-being among youth offenders in Singapore, according to a recent study.
A 3-day inaugural hackathon organized by the pharmaceutical division of Roche (Malaysia) Sdn. Bhd. among its employees has resulted in two potential educational initiatives for cancer patients in Malaysia.
Treatment with cannabidiol led to a significant reduction in the frequency of seizures in children and adults with tuberous sclerosis complex (TSC), according to the GWPCARE6* study.
Daily intake of cow’s milk formula in early life helps prevent the development of cow’s milk allergy later on without competing with breastfeeding, a recent study has found.
Special Reports
Despite a 90-percent cure rate after first treatment for children with acute lymphoblastic leukaemia (ALL), approximately 10–15 percent of patients with paediatric ALL will experience relapse. [Expert Rev Anticancer Ther 2017;17:725-736] A recent webinar on the current landscape of ALL highlighted the potential of immunotherapy for paediatric patients with relapsed or refractory ALL, thus providing hope for this high-risk patient group.
Acute diarrhoea is the second leading cause of deathin children aged younger than 5 years, accounting forapproximately 1.9 million deaths worldwide each year;however, diarrhoea is a preventable and treatable condition.In Malaysia, acute gastroenteritis accounts for about 1.3%of all deaths in children aged younger than 5 years annually.Diarrhoea is defined as the passage of three or more looseor watery stools within 24 hours, and it may be clinicallycategorised as either acute watery diarrhoea (AWD), acutebloody diarrhoea, persistent diarrhoea or diarrhoea withsevere malnutrition.
Rotavirus (RV) is highly contagious. Globally, 2 million children are hospitalized and more than 500,000 die annually from RV associated gastroenteritis. Therefore, vaccination is imperative for the prevention of RV infections.
Oral H1-antihistamines are the initial treatment of choice for allergic rhinitis (AR) and chronic urticaria in the primary care setting. However, in a diverse population of patients with AR and urticaria, primary care physicians are faced with the challenge of prescribing the best therapy amid a wide armamentarium of antihistamines available.
In conjunction with the launch of QV Intensive with Ceramides (Ego Pharm), the important role of ceramides in themanagement of atopic dermatitis (AD) was highlighted by two distinguished speakers, Dr Agnes Heng of KPJ and Pantai Hospital Ipoh, as well as Dr Fabrizio Spada of Ego Pharmaceuticals, Australia.
SKYCELLFLU – Inactivated quadrivalent influenza vaccine (inj) 0.5 mL - AJ Biologics
Gangliosides and docosahexaenoic acid (DHA) play critical roles in early childhood brain development.
Conference Reports
Adolescents with obesity who undergo sleeve gastrectomy may be at risk of poor bone health, according to a small study presented at the recent annual meeting of the Radiological Society of North America (RSNA 2020).
The timing of betamethasone (BMZ) administration in pregnant women does not seem to differentially affect the suppression of the hypothalamic-pituitary-adrenal (HPA) axis and, in turn, has no apparent effect on neonatal outcomes, according to a study presented at recently concluded 40th Annual Pregnancy Meeting of the Society for Maternal Foetal Medicine (SMFM 2020).
Slideshow: Highlights from the American Thoracic Society 2019 (ATS 2019) International Conference
Podcast: Professor Oliver Distler talks about the utility of nintedanib in ILD in the SENSCIS trial
Increased exposure to secondhand tobacco smoke (SHS) was significantly associated with an elevated blood pressure (BP) in children and adolescents, according to a study presented at PAS* 2019 Meeting.
The low uptake of the human papillomavirus (HPV) vaccine in the US and strategies to improve HPV vaccine coverage were highlighted in two studies presented at the Pediatric Academic Societies annual meeting (PAS 2019).
A 26-week regimen of liraglutide effectively improved glycaemic control in adolescents with type 2 diabetes (T2D) who had inadequate response to metformin, according to the results of the phase III Ellipse* trial presented as a poster at the recent Pediatric Academic Societies meeting (PAS 2019).
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