Paediatrics

Top Medical News
Onasemnogene abeparvovec for spinal muscular atrophy safe in heavier babies
2 hours ago
Babies who weigh ≥8.5 kg can safely be administered with onasemnogene abeparvovec for the treatment of spinal muscular atrophy, a new study has found.
Dextrose gel reduces need for intravenous fluids in babies with asymptomatic hypoglycaemia
12 hours ago
In neonates who have asymptomatic hypoglycaemia in the first 48 hours of life, administering dextrose gel is useful and minimizes requirement for intravenous fluids, as shown in a study.
Newborn screening facilitates timely detection, treatment of late-onset Pompe disease
14 hours ago
In one-fifth of patients, late-onset Pompe disease (LOPD) manifests within 15 years of detection, a recent study has found. Newborn screening (NBS) can help detect LOPD early despite having no symptoms, and may lead to timely treatment administration.
Isolated systolic hypertension tied to increased LV mass index, aortic stiffness in adolescents
3 days ago
Adolescents with isolated systolic hypertension (ISH), including the spurious hypertension (sHTN) subtype, show more noticeable markers of cardiac end-organ damage, higher aortic stiffness, and stroke volume than those with white-coat hypertension (WCH), a study has shown.
Male sex, obesity among risk factors for severe COVID-19 in children
Roshini Claire Anthony, 4 days ago

A large study by the US National COVID Cohort Collaborative (N3C) has identified factors associated with the risk of severe disease among children with SARS-CoV-2 infection as well as factors tied to an increased risk of multisystem inflammatory syndrome in children (MIS-C) as compared to acute COVID-19.

Antidepressant exposure in pregnancy not a risk factor for neonatal seizures, epilepsy
Jairia Dela Cruz, 4 days ago
In pregnant women, the use of serotonergic antidepressants does not appear to put babies at risk of developing seizures or epilepsy, as reported in a study.
Nasal microbiome predicts bronchopulmonary dysplasia in preterm infants
5 days ago
In infants born preterm, the nasal microbiome seems to correlate with the incidence and severity of bronchopulmonary dysplasia, reports a recent study.
Special Reports
Product Highlight - Bilaxten ODT
16 Mar 2022
Bilastine 10 mg orodispersible tablet
Kids hard-hit by Delta; which ART performs best?
Elvira Manzano, 24 Oct 2021
That COVID-19 mostly spared children might be changing. The Delta variant has taken a severe, unthinkable toll on kids – at least in Arkansas, US, reports an expert at IDWeek 2021.
ID NOW rapid molecular assay an effective COVID-19 test for kids
Roshini Claire Anthony, 20 Oct 2021

A large retrospective study from the US, presented at IDWeek 2021, has shown that the Abbott ID NOW rapid molecular COVID-19 assay is highly sensitive and specific at detecting SARS-CoV-2 infection in a paediatric population.

Combined Ag/Ab rapid testing boosts case-finding in COVID-19
Elvira Manzano, 29 Jul 2021
A rapid and affordable test for diagnosing COVID-19 outside the walls of the healthcare units could improve case-finding, contact tracing, and infection control, says an expert during a pre-ECCMID 2021 session.
Product Highlight - Zinforo
16 Jun 2021
Ceftaroline fosamil 600 mg powder for infusion
Navigating the CPP patient journey – case-based discussion for nurses
06 May 2021
In a webinar held on 27 March 2021, paediatric endocrinology nurses Karen Blair, Kate Davies, and Siti Zarina Yaakop shared insights and clinical experience based on their frontline roles in caring for patients with central precocious puberty (CPP) and supporting their family members.
A Guide on Primary Immunodeficiency Disease and Allergies
05 Feb 2021

Primary immunodeficiency disease (PIDD) and allergies are two groups of conditions related to the immune system. However, they are uniquely different in terms of symptoms and treatment.

Conference Reports
Timing of maternal antibiotic administration affects infant gut microbiome
Audrey Abella, 28 Jun 2021
Maternal administration of antibiotics prior to Caesarean section (CS) disrupts infant microbial colonization, according to the findings of the MAMI* trial presented at WCPGHAN 2021.
Bioactive nutrient-enriched infant formula may enhance neurocognitive outcomes
Elaine Soliven, 22 Jun 2021
A new infant formula supplemented with bioactive nutrients — containing MFGM* components, LC-PUFAs**, and synbiotics — may improve neurocognitive function and brain development in healthy children at 6 years of age, according to the COGNIS*** study presented at WCPGHAN 2021.
New anti-regurgitation formula confers benefit for infants with severe GI burden
Audrey Abella, 21 Jun 2021
A novel anti-regurgitation (AR) formula combining carob bean gum (CBG) with prebiotics and postbiotics was found to have a more pronounced benefit for infants with more severe gastrointestinal (GI) symptoms, according to the results of a post hoc analysis presented at WCPGHAN 2021.
Undiagnosed coeliac disease in children common, indicates need for widespread screening
Jairia Dela Cruz, 14 Jun 2021
Coeliac disease cases among school age children have doubled over two and a half decades, and without a wider screening strategy, most cases will remain undiagnosed, as shown in the CELI SCREEN trial.
Mothers passing on HBV to children due to patchy hospital policies across Europe
Stephen Padilla, 14 Jun 2021
A recent European survey has found major discrepancies and gaps in hospital policies and procedures to prevent the direct transmission of hepatitis B virus (HBV) from mother to child, particularly before and after birth.
Omega-3 supplements may up risk of AF
Elvira Manzano, 09 Jun 2021
Children whose mothers had taken fish oil supplements during the second half of pregnancy appeared to have better problem-solving skills and attention focus at age 10 vs those whose mothers had consumed folic acid alone or no supplements at all in a study presented at WCPGHAN 2021.
Dupilumab an alternative for children with severe AD
Audrey Abella, 19 May 2021
The addition of the monoclonal antibody dupilumab to a standard topical corticosteroid (TCS) regimen led to significant improvements in scoring AD (SCORAD*) and its components, as well as EASI** scores, in children with severe atopic dermatitis (AD), according to data from the phase III LIBERTY AD PEDS trial presented at PAS 2021.