Paediatrics

ADHD medication use carries no excess risk of cardiovascular diseases

Yesterday

Users of attention-deficit/hyperactivity disorder (ADHD) medications across age groups do not appear to be at increased risk of cardiovascular diseases (CVDs), although a modest risk increase of cardiac arrest or tachyarrhythmias could not be ruled out, according to the results of a meta-analysis.

Pharmacogenomic profiling of paediatric AML informs precision medicine

Natalia Reoutova, Yesterday

A study by the Chinese University of Hong Kong (CUHK) has found age-specific differences in drug responses and new gene-drug interactions in paediatric acute myeloid leukaemia (AML).

High-flow nasal cannula oxygen therapy better than CPAP in preterm infants

Tristan Manalac, 4 days ago

Compared with continuous positive airway pressure (CPAP), respiratory support using high-flow nasal cannula oxygen therapy (HNFC) appears to yield better clinical outcomes in preterm infants, according to a recent meta-analysis.

CGM improves HbA1c levels in T1D

Roshini Claire Anthony, 5 days ago

Continuous glucose monitoring (CGM) with alarms for high or low blood sugar levels better controlled HbA_1c levels than personal fingerstick monitoring in patients with type 1 diabetes (T1D), results of the FLASH-UK trial showed.

ID NOW rapid molecular assay an effective COVID-19 test for kids

Rapid COVID-19 testing: Is it as good in kids?

Roshini Claire Anthony, 20 Oct 2021

A large retrospective study from the US, presented at IDWeek 2021, has shown that the Abbott ID NOW rapid molecular COVID-19 assay is highly sensitive and specific at detecting SARS-CoV-2 infection in a paediatric population.

Combined Ag/Ab rapid testing boosts case-finding in COVID-19

Elvira Manzano, 29 Jul 2021

A rapid and affordable test for diagnosing COVID-19 outside the walls of the healthcare units could improve case-finding, contact tracing, and infection control, says an expert during a pre-ECCMID 2021 session.

Navigating the CPP patient journey – case-based discussion for nurses

06 May 2021

In a webinar held on 27 March 2021, paediatric endocrinology nurses Karen Blair, Kate Davies, and Siti Zarina Yaakop shared insights and clinical experience based on their frontline roles in caring for patients with central precocious puberty (CPP) and supporting their family members.

Ruxolitinib improves repigmentation in vitiligo through 52 weeks

Elaine Soliven, 21 Oct 2022

Long-term use of ruxolitinib cream continued to improve facial and total body repigmentation in patients with nonsegmental vitiligo from 24 to 52 weeks, according to an updated pooled analysis of the phase III TRuE-V1* and TRuE-V2** studies presented at EADV 2022.

Lebrikizumab efficacy in atopic dermatitis maintained at 1 year

Roshini Claire Anthony, 12 Oct 2022

Maintenance lebrikizumab monotherapy appears to improve outcomes in patients with moderate-to-severe atopic dermatitis (AD), according to results of the phase III ADvocate1 and ADvocate2 trials.

ALLEGRO-LT shows long-term benefit of ritlecitinib for alopecia areata

Audrey Abella, 21 Sep 2022

In the interim analysis of the ongoing phase III ALLEGRO-LT trial, the investigational oral JAK3*/TEC inhibitor ritlecitinib demonstrated long-term safety and remarkable scalp hair regrowth in adults and adolescents with alopecia areata (AA).

Similar asthma outcomes, but higher allergy rates, in ART-conceived children

Elaine Soliven, 11 Aug 2022

Children conceived through assisted reproductive technology (ART) showed similar asthma outcomes but had a higher risk of allergies and slightly altered lung function compared with those who were born after spontaneous conception, according to a study presented at ESHRE 2022.

Timing of maternal antibiotic administration affects infant gut microbiome

Audrey Abella, 28 Jun 2021

Maternal administration of antibiotics prior to Caesarean section (CS) disrupts infant microbial colonization, according to the findings of the MAMI* trial presented at WCPGHAN 2021.

Bioactive nutrient-enriched infant formula may enhance neurocognitive outcomes

Elaine Soliven, 22 Jun 2021

A new infant formula supplemented with bioactive nutrients — containing MFGM* components, LC-PUFAs**, and synbiotics — may improve neurocognitive function and brain development in healthy children at 6 years of age, according to the COGNIS*** study presented at WCPGHAN 2021.