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Paediatrics
Top Medical News
Children born to women who smoked during pregnancy are at high risk of developing a wheeze and having decreased lung function, according to the results of a systematic review and meta-analysis.
Investigational drug AMO-02 (tideglusib) has a favourable risk-benefit and pharmacokinetic profile for congenital and childhood-onset type 1 myotonic dystrophy, a recent phase II study has shown. Further studies on tideglusib are warranted.
While most children with agenesis of the corpus callosum (ACC) enjoy good developmental outcomes, individual outcomes remain difficult to predict, a new study has found.
Having vaccination against influenza during pregnancy was not associated with an increased risk of autism spectrum disorder (ASD) in the offspring, a large cohort study reveals — providing more support for vaccination during pregnancy.
Children with bladder bowel dysfunction fare well with combined pelvic floor interferential electrical stimulation and muscle exercises, which can lead to a significant decrease in daytime incontinence, urgency, and constipation, as shown in a study.
In paediatric patients with microbial keratitis, the most significant risk factors are contact lens wear, trauma, and existing ocular disease, while pre-existing corneal disease and delay in presentation correlate with poor visual acuity, according to a study.
Thyroid dysfunction during pregnancy is associated with several neurocognitive outcomes in the offspring, suggest the results of a study. Prompt examination and treatment on thyroid function is urged for pregnant women.
Special Reports
Despite a 90-percent cure rate after first treatment for children with acute lymphoblastic leukaemia (ALL), approximately 10–15 percent of patients with paediatric ALL will experience relapse. [Expert Rev Anticancer Ther 2017;17:725-736] A recent webinar on the current landscape of ALL highlighted the potential of immunotherapy for paediatric patients with relapsed or refractory ALL, thus providing hope for this high-risk patient group.
Acute diarrhoea is the second leading cause of deathin children aged younger than 5 years, accounting forapproximately 1.9 million deaths worldwide each year;however, diarrhoea is a preventable and treatable condition.In Malaysia, acute gastroenteritis accounts for about 1.3%of all deaths in children aged younger than 5 years annually.Diarrhoea is defined as the passage of three or more looseor watery stools within 24 hours, and it may be clinicallycategorised as either acute watery diarrhoea (AWD), acutebloody diarrhoea, persistent diarrhoea or diarrhoea withsevere malnutrition.
Rotavirus (RV) is highly contagious. Globally, 2 million children are hospitalized and more than 500,000 die annually from RV associated gastroenteritis. Therefore, vaccination is imperative for the prevention of RV infections.
Oral H1-antihistamines are the initial treatment of choice for allergic rhinitis (AR) and chronic urticaria in the primary care setting. However, in a diverse population of patients with AR and urticaria, primary care physicians are faced with the challenge of prescribing the best therapy amid a wide armamentarium of antihistamines available.
In conjunction with the launch of QV Intensive with Ceramides (Ego Pharm), the important role of ceramides in themanagement of atopic dermatitis (AD) was highlighted by two distinguished speakers, Dr Agnes Heng of KPJ and Pantai Hospital Ipoh, as well as Dr Fabrizio Spada of Ego Pharmaceuticals, Australia.
At the 40th Malaysian Paediatric Association Annual Congress held on 6 September 2018 at the Ipoh Convention Centre, Dr Yong Junina Fadzil discussed the applications of a hexavalent vaccine in optimizing paediatric vaccination schedules. Meanwhile, Dato’ Dr Musa Mohd Nordin shared his insights into the paediatric influenza ‘landscape’ in the region and highlighted the importance of regularly vaccinating paediatric patients.
SKYCELLFLU – Inactivated quadrivalent influenza vaccine (inj) 0.5 mL - AJ Biologics
Conference Reports
The timing of betamethasone (BMZ) administration in pregnant women does not seem to differentially affect the suppression of the hypothalamic-pituitary-adrenal (HPA) axis and, in turn, has no apparent effect on neonatal outcomes, according to a study presented at recently concluded 40th Annual Pregnancy Meeting of the Society for Maternal Foetal Medicine (SMFM 2020).
Slideshow: Highlights from the American Thoracic Society 2019 (ATS 2019) International Conference
Podcast: Professor Oliver Distler talks about the utility of nintedanib in ILD in the SENSCIS trial
Increased exposure to secondhand tobacco smoke (SHS) was significantly associated with an elevated blood pressure (BP) in children and adolescents, according to a study presented at PAS* 2019 Meeting.
The low uptake of the human papillomavirus (HPV) vaccine in the US and strategies to improve HPV vaccine coverage were highlighted in two studies presented at the Pediatric Academic Societies annual meeting (PAS 2019).
A 26-week regimen of liraglutide effectively improved glycaemic control in adolescents with type 2 diabetes (T2D) who had inadequate response to metformin, according to the results of the phase III Ellipse* trial presented as a poster at the recent Pediatric Academic Societies meeting (PAS 2019).
The use of text messaging as a reminder for the next human papillomavirus (HPV) vaccine dose may help increase the rates of HPV vaccine series completion, according to a study presented at PAS* 2019 Meeting.
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