Overactive bladder or non-neurogenic overactive bladder is a syndrome characterized by urinary urgency, frequency, nocturia and urgency incontinence.
It is not a disease but a symptom complex that generally is not a life-threatening condition. It is also known as bladder spasms.
Urgency is the complaint of sudden, compelling desire to pass urine that is difficult to deny. It is considered a hallmark symptom of overactive bladder.
Frequency is usually micturition of >7 episodes during waking hours.
Nocturia is the interruption of sleep one or more times because of the need to void.
Urgency incontinence is the involuntary leakage of urine associated with a sudden compelling desire to void.
Single weekly sessions of parasacral transcutaneous electrical neural stimulation (PTENS) show potential in the treatment of paediatric overactive bladder (OAB), producing improvements in urinary urgency and enuresis, a study has shown.
Frequent nocturia episodes, a suboptimal response, and small bladder capacity appear to predict the need for persistent antimuscarinic therapy or re-treatment after solifenacin treatment in women with overactive bladder syndrome, according to a study.
Repeat treatments with onabotulinumtoxinA appear to produce consistent improvements in urinary symptoms and quality of life (QOL) for 3.5 years in patients with overactive bladder (OAB) and urinary incontinence (UI), according to a study.
Systolic blood pressure appears to have a strong association with aneurysmal subarachnoid haemorrhage (aSAH) but not with unruptured intracranial aneurysm (UIA), whereas current smoking and female sex are risk factors for both conditions, a study has found.