Overactive bladder or non-neurogenic overactive bladder is a syndrome characterized by urinary urgency, frequency, nocturia and urgency incontinence.
It is not a disease but a symptom complex that generally is not a life-threatening condition. It is also known as bladder spasms.
Urgency is the complaint of sudden, compelling desire to pass urine that is difficult to deny. It is considered a hallmark symptom of overactive bladder.
Frequency is usually micturition of >7 episodes during waking hours.
Nocturia is the interruption of sleep one or more times because of the need to void.
Urgency incontinence is the involuntary leakage of urine associated with a sudden compelling desire to void.
Single weekly sessions of parasacral transcutaneous electrical neural stimulation (PTENS) show potential in the treatment of paediatric overactive bladder (OAB), producing improvements in urinary urgency and enuresis, a study has shown.
Frequent nocturia episodes, a suboptimal response, and small bladder capacity appear to predict the need for persistent antimuscarinic therapy or re-treatment after solifenacin treatment in women with overactive bladder syndrome, according to a study.
Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.
Implementation of the collaborative care in a rheumatoid arthritis (RA) clinic has led to improvements in nonbiologic disease-modifying antirheumatic drugs (nb-DMARDs) optimization, adherence to safety recommendations on nb-DMARD monitoring and detection of adverse drug events in RA patients, according to a Singapore study.
Supplementation with vitamin D appears to help reduce the serum concentration of total and low-density lipoprotein cholesterol and triglyceride but not high-density lipoprotein cholesterol, suggesting its usefulness for mitigating the risk of cardiovascular disease in patients with hypercholesterolaemia, according to the results of a meta-analysis.