Otitis media is a general term used to describe inflammation of the middle ear which may be caused by an acute infection.
The symptoms are usually nonspecific and include otalgia (pulling of ear in an infant), irritability, otorrhea with or without fever.
Symptoms of upper respiratory tract infection may also be present
In children with recurrent acute otitis media (rAOM), the presence of bacterial otopathogen, particularly nontypeable H. influenzae (NTHi), in the middle ear during ventilation tube insertion (VTI) is associated with repeat surgery, according to a recent study.
Children who undergo adenoidectomy, tonsillectomy, or both (adenotonsillectomy) within the first 9 years of life may have an elevated long-term risk of respiratory, allergic, or infectious diseases, results from a Denmark-based study show.
Despite a 90-percent cure rate after first treatment for children with acute lymphoblastic leukaemia (ALL), approximately 10–15 percent of patients with paediatric ALL will experience relapse. [Expert Rev Anticancer Ther 2017;17:725-736] A recent webinar on the current landscape of ALL highlighted the potential of immunotherapy for paediatric patients with relapsed or refractory ALL, thus providing hope for this high-risk patient group.