osteoporosis
OSTEOPOROSIS
Osteoporosis is the progressive, systemic skeletal disease characterized by decreased bone mass and micro-architectural deterioration of bone tissue leading to bone fragility and increased susceptibility to fractures.
The more risk factors (eg history, of fracture, advanced age, comorbidities, impaired vision) that are present, the greater the risk of fracture.

Differential Diagnosis

  • Pathological fracture
  • Secondary osteoporosis
Causes of Secondary Osteoporosis
  • Endocrine diseases [eg Cushing’s syndrome, hypogonadism (mostly in men), hyperthyroidism, hyperparathyroidism, etc]
  • Medications (eg corticosteroids, Heparin, anticonvulsants, immunosuppressants, excessive alcohol, etc)
  • Chronic diseases (eg renal impairment, liver cirrhosis, malabsorption, etc)
  • Others (eg malnutrition, malignancy, etc)
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