Osteoporosis is the progressive, systemic skeletal disease characterized by decreased bone mass and micro-architectural deterioration of bone tissue leading to bone fragility and increased susceptibility to fractures.
The more risk factors (eg history, of fracture, advanced age, comorbidities, impaired vision) that are present, the greater the risk of fracture.

Differential Diagnosis

  • Pathological fracture
  • Secondary osteoporosis
Causes of Secondary Osteoporosis
  • Endocrine diseases [eg Cushing’s syndrome, hypogonadism (mostly in men), hyperthyroidism, hyperparathyroidism, etc]
  • Medications (eg corticosteroids, Heparin, anticonvulsants, immunosuppressants, excessive alcohol, etc)
  • Chronic diseases (eg renal impairment, liver cirrhosis, malabsorption, etc)
  • Others (eg malnutrition, malignancy, etc)
Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Endocrinology - Malaysia digital copy today!
Editor's Recommendations
Most Read Articles
Pank Jit Sin, 4 days ago
Empagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, recently received the National Pharmaceutical Regulatory Agency’s approval for an update on its indication.