The addition of intrastromal voriconazole (ISV) to topical natamycin does not appear to provide any benefit in the primary treatment of moderate-to-severe filamentous fungal ulcers, a recent study in India has found.
Long-term intraocular pressure (IOP) fluctuation, greater vertical cup-to-disc ratio (v-C/D), and the presence or history of disc haemorrhage (DH) are significantly associated with progression of normal-tension glaucoma (NTG), suggests a study involving Japanese patients.
Asians who use angiotensin-converting enzyme inhibitors, fibrates, alpha-glucosidase inhibitors or insulin are likely to have cortical cataract, independent of the presence of hypertension, hyperlipidaemia or diabetes, according to data from the Singapore Epidemiology of Eye Diseases (SEED) study.
The fixed-dose combination of brinzolamide 1% and brimonidine 0.2% (BBFC) is superior to vehicle in lowering intraocular pressure (IOP) over a 24-hour period following 4 weeks of 3-times-daily treatment in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT), a study has shown.
A novel incentive strategy which rewards patients who are compliant to their medications significantly improves adherence rates, thus providing a potential cost-effective adherence intervention, the SIGMA* study shows.
Normal-tension glaucoma patients with low night-time through diastolic blood pressure (DBP) are at heightened risk of visual field progression, and this risk is associated with the duration and magnitude of nocturnal DBP dip, a study has found.
Greater physical activity, such as increased walking and more time spent doing moderate-to-vigorous or nonsedentary activity, may reduce visual field (VF) loss in a treated population of patients with glaucoma, a study has found. Moreover, adding 5,000 daily steps or 2.6 hours of nonsedentary physical activity decreases the average rate of VF by 10 percent.
Use of intravitreal antivascular endothelial growth factor (anti-VEGF) therapy in patients with diabetic macular oedema (DME) in routine clinical practice does not escalate the hazard of cerebrovascular disease, myocardial infarction or major bleeding within 6 months after treatment, reports a study.
Exposure to corticosteroids in patients with autoimmune hepatitis (AIH) appears to contribute to increased risks of cataract, diabetes and bone fractures, a study has found. Notably, the fracture risk is elevated at low doses, while the risk of adverse events overall is dose-dependent and is reversible.
In patients with atrial fibrillation (AF) and stable coronary artery disease (CAD), rivaroxaban monotherapy is noninferior to combination treatment with an antiplatelet therapy in terms of cutting the risk of cardiovascular events and mortality, according to data from the AFIRE trial.
Supplementation with oral nano vitamin D appears to moderate disease activity and severity grade of patients with active ulcerative colitis (UC), suggests a study, adding that this association is more evident in those achieving a target vitamin D level of 40 ng/mL.