New drug applications approved by US FDA as of 1 - 15 November 2017 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
The presence of corneal arcus in Indian and Malay men appears to be associated with the risk of incident cardiovascular disease (CVD), independent of serum lipids and traditional CVD risk factors, reports a team of Singapore-based researchers.
The presence of vitreous haze, snow banking, and choroidal involvement is associated with an increased risk of antitubercular treatment failure in patients with tubercular (TB) uveitis, according to research by the COTS-1* Study Group.
Fluocinolone acetonide implant and systemic corticosteroid therapy both improve vision-related quality of life (VRQoL) in patients with noninfectious uveitis, according to a study. However, the implant group shows an immediate improvement as compared to gradual for the systemic group.
In diabetic macular oedema (DME), visual outcomes following intravitreal dexamethasone implant therapy may be predicted by early treatment response, according to a study. Specifically, eyes with optimal early responses demonstrate better outcomes compared with eyes having suboptimal early visual acuity gains.
It appears that allotopic gene therapy at low and medium doses is safe and does not damage the temporal retinal nerve fibre layer in patients with Leber hereditary optic neuropathy (LHON), paving the way for testing of the high dose, according to a new study.
Subtracting the original retinal thickness from the combined choroid-retina thickness to calculate the mean choroidal thickness (CT) is an easier and reliable method compared with the manual segmentation of optical coherence tomography (OCT) B-scans, a recent Singapore study has shown.
In Asian patients taking hydroxychloroquine (HCQ) medications, there appears to be a pericentral distribution of retinopathy identified using wide-field optical coherence tomography (OCT) but not with standard OCT protocols, according to a study.
The baseline inferior subfield retinal thickness may predict the frequency of treatment for diabetic macular oedema (DME) during the first year in eyes administered pro re nata (PRN) intravitreal ranibizumab (IVR) injections, a new study shows.