The use of microscope-integrated intraoperative optical coherence tomography (iOCT) is feasible and helpful during ophthalmic surgery based on the surgeon-reported impact on surgical decision-making, reports a study.
Treatment with adalimumab leads to quiescence, improved visual acuity and reduced daily uveitis-related systemic corticosteroid use in patients with active uveitis and sustained quiescence without a systemic corticosteroid dose increase among those with inactive uveitis at study entry, results of the VISUAL III trial have shown. Additionally, no new safety signals are found.
Low-dose bevacizumab yields excellent retinal structural outcomes in the treatment of retinopathy of prematurity, although a number of infants may still require additional treatment, as shown in a study.
Intravitreal aflibercept injection appears to be safe and effective in the treatment of polypoidal choroidal vasculopathy, producing improvements in visual and/or functional outcomes without any signs of leakage lesions in most patients, according to the results of the PLANET study.
Plasma sex hormone concentration overall does not have any effect on the risk of primary open-angle glaucoma (POAG) in postmenopausal women, according to a study. However, elevated testosterone levels appear to be associated with POAG and higher intraocular pressure (IOP).
A dual-hormone artificial pancreas (DAP) with a rapid delivery of insulin and pramlintide in a fixed ratio improves glycaemic control and reduces glucose variability in adults with type 1 diabetes (T1D) compared with first-generation artificial pancreas delivering insulin alone, according to a study presented at ADA 2018.
More intensive lowering of LDL-C levels was associated with a progressively greater survival benefit than less intensive approach, when the baseline LDL-C levels were ≥100 mg/dL, reveals a meta-analysis of 34 randomized trials.