The biomechanical response of the optic nerve head (ONH) appears to be related to disease severity in eyes with primary open-angle glaucoma (POAG), but not primary angle-closure glaucoma (PACG), a recent Singapore study has found.
Meibomian gland dysfunction is associated with lower tear meniscus area, while older age corresponds to a more severe conjunctivochalasis, a recent Singapore study has shown. This suggests that anterior segment optical coherence tomography may be useful in assessing ocular surface tear function and tear volume.
A vestibular rehabilitation programme (BEEMS*) integrating balance and eye movement exercises can help improve balance, dizziness, and fatigue in patients with multiple sclerosis (MS), who commonly encountered these problems which can lead to falls and limited mobility, according to a new study.
Despite guidelines advocating stroke risk factor assessment following retinal infarction (stroke of the eye), adherence to the guidelines within 90 days of infarct was poor among elderly patients, leading to a potentially elevated risk of stroke, according to a study presented at the recent International Stroke Conference 2018 (ISC 2018) in Los Angeles, California, US.
Highly myopic Asian adolescents show significant progression of the disease and of retinal and disc lesions, such as incident fundus tessellation and optic disc tilt, according to a recent Singapore study.
Of the newly identified genetic loci for primary angle-closure glaucoma (PACG), two are significantly associated with primary angle-closure suspect (PACS), indicating involvement in the earlier stages of the disease, a recent Singapore study has shown.
drug applications approved by US FDA as of 1 - 15 February 2018 which includes
Entities (NMEs) and new biologics. It does not include Tentative Approvals.
Supplemental approvals may have occurred since the original approval date.
Macrolide antibiotics are derived from the Streptomycesspecies. These contain either 14-membered (erythromycin [ERM],clarithromycin [CAM], roxithromycin [RXM]), 15-membered(azithromycin [AZM]) or 16-membered (spiramycin, josamycin,midecamycin) macrocyclic lactone rings. They inhibit proteinsynthesis by reversibly binding to the 23S ribosomal RNA (rRNA)in the 50s subunit of the bacterial ribosome. Traditionally,macrolides are used as first-line agents in respiratory, skin,soft tissue, and urogenital infections, and they are also activeagainst gram-positive cocci and atypical pathogens.
Pneumonia is a common infection– affecting around 3,200 people inSingapore in 2016 – making it the thirdmost common cause of hospitalisation inthe country. Its common complications,especially with delayed or inappropriatetreatment, include bacteraemia andseptic shock, lung abscesses, pleuraleffusions, empyema, pleurisy, respiratoryfailure and renal failure.
Higher concentrations of distinct ceramide species, known to be linked to adverse metabolic health, are associated with cumulative sugar-sweetened beverage (SSB) consumption that contributes to the development of cardiometabolic diseases, suggests a study.