Children spending longer hours in cram school are at greater risk of myopia, with the effect attributed to increased time doing near visual activity or reduced time spent outdoors, a Taiwan study has found.
Treatment with adalimumab leads to quiescence, improved visual acuity and reduced daily uveitis-related systemic corticosteroid use in patients with active uveitis and sustained quiescence without a systemic corticosteroid dose increase among those with inactive uveitis at study entry, results of the VISUAL III trial have shown. Additionally, no new safety signals are found.
Intravitreal aflibercept injection appears to be safe and effective in the treatment of polypoidal choroidal vasculopathy, producing improvements in visual and/or functional outcomes without any signs of leakage lesions in most patients, according to the results of the PLANET study.
Children in Singapore were exposed to significantly less outdoor light daily than children in Australia, which could contribute to the higher prevalence of myopia among Singapore children compared with their Australian counterparts, suggests a study.
Individuals with diabetes or long-term hyperglycaemia appear to have higher intraocular pressure (IOP), with central corneal thickness representing a meagre proportion of mediating effect to the total effect of diabetes on IOP, according to a cross-sectional study from Singapore.
Silent reading for as little as 30 minutes may induce measurable changes on the tear film and ocular surface in individuals at least 50 years of age, especially in those with dry eye, a study has found.
Long-term consumption of the green tea cultivar Sunrouge led to significant improvement in accommodation ability (AA, ie, focusing ability of the eye) and eyestrain among healthy adults under 45 years and those who operated visual display terminals (VDTs, ie, computers, smartphones, or tablets) daily, according to a Japanese study.
Panretinal photocoagulation (PRP) plus ranibizumab (RBZ) is more effective than PRP monotherapy for neovascularization (NV) regression in the eyes of patients with high-risk proliferative diabetic retinopathy (HR-PDR) over a 12-month period, according to a phase II/III study. Additionally, the combination therapy poses no safety concerns.
Eating dark chocolates may have short-term beneficial impacts on vision, according to a recent study, which reports significant improvements in contrast sensitivity and visual acuity following dark vs milk chocolate consumption.
Macrolide antibiotics are derived from the Streptomycesspecies. These contain either 14-membered (erythromycin [ERM],clarithromycin [CAM], roxithromycin [RXM]), 15-membered(azithromycin [AZM]) or 16-membered (spiramycin, josamycin,midecamycin) macrocyclic lactone rings. They inhibit proteinsynthesis by reversibly binding to the 23S ribosomal RNA (rRNA)in the 50s subunit of the bacterial ribosome. Traditionally,macrolides are used as first-line agents in respiratory, skin,soft tissue, and urogenital infections, and they are also activeagainst gram-positive cocci and atypical pathogens.
Nonsmall cell lung cancer (NSCLC) patients harbouring sensitive EGFR mutations may fare well with the third-generation tyrosine kinase inhibitor osimertinib as an upfront therapy, with the results of a network meta-analysis showing that the drug tops other currently available options in terms of progression-free survival and tolerability.
Pneumonia is a common infection– affecting around 3,200 people inSingapore in 2016 – making it the thirdmost common cause of hospitalisation inthe country. Its common complications,especially with delayed or inappropriatetreatment, include bacteraemia andseptic shock, lung abscesses, pleuraleffusions, empyema, pleurisy, respiratoryfailure and renal failure.