Diabetic retinopathy is a leading cause of blindness, making early detection of this condition crucial. Dr Yong Shao Onn from the Eagle Eye Centre at Mt Alvernia Hospital, Singapore, speaks to Roshini Claire Anthony on the diagnosis and treatment options.
Intravitreal injection of antivascular endothelial growth factor (anti-VEGF) therapy is a safe and effective treatment for neovascular age-related macular degeneration (AMD) over 2 years, the period for which data are available in this literature review.
A conbercept dosing regimen of three initial monthly intravitreal injections followed by quarterly treatments appears to be effective in the treatment of neovascular age-related macular degeneration (AMD), yielding visual and anatomic benefits at 3 and 12 months, according to data from the PHOENIX trial.
One in 10 Malay, Indian and Chinese Singaporeans aged ≥40 years undergoes cataract surgery in at least one eye over 6 years, according to data from the Singapore Epidemiology of Eye Diseases (SEED) Study. Diabetes and myopia are modifiable risk factors for cataract prevalence.
The MGDRx EyeBag, a device designed to treat meibomian gland dysfunction, effectively relieves dry eye symptoms, according to a recent study. However, there seems to be little effect on MG function and tear stability.
New drug applications approved by US FDA as of 1 - 15 October 2018 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Macrolide antibiotics are derived from the Streptomycesspecies. These contain either 14-membered (erythromycin [ERM],clarithromycin [CAM], roxithromycin [RXM]), 15-membered(azithromycin [AZM]) or 16-membered (spiramycin, josamycin,midecamycin) macrocyclic lactone rings. They inhibit proteinsynthesis by reversibly binding to the 23S ribosomal RNA (rRNA)in the 50s subunit of the bacterial ribosome. Traditionally,macrolides are used as first-line agents in respiratory, skin,soft tissue, and urogenital infections, and they are also activeagainst gram-positive cocci and atypical pathogens.
Pneumonia is a common infection– affecting around 3,200 people inSingapore in 2016 – making it the thirdmost common cause of hospitalisation inthe country. Its common complications,especially with delayed or inappropriatetreatment, include bacteraemia andseptic shock, lung abscesses, pleuraleffusions, empyema, pleurisy, respiratoryfailure and renal failure.
Higher concentrations of distinct ceramide species, known to be linked to adverse metabolic health, are associated with cumulative sugar-sweetened beverage (SSB) consumption that contributes to the development of cardiometabolic diseases, suggests a study.