A triple fixed combination of bimatoprost 0.01%/brimonidine 0.15%/timolol 0.5% ophthalmic solution provides superior intraocular pressure (IOP)-lowering effects compared with a dual fixed combination of brimonidine 0.2%/timolol 0.5% in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OHT), according to the results of a phase III study.
When choosing between ranibizumab and aflibercept for treating neovascular age-related macular degeneration, neither drug bests the other in terms of visual acuity outcomes and treatment frequency at 3 years, according to data from the Fight Retinal Blindness! Registry.
New drug applications approved by US FDA as of 01 - 15 March 2020 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.
Damage to small blood vessels of the eye appears to be a significant marker for an increased risk of stroke in patients with diabetes, suggesting that the microvascular pathology inherent to diabetic retinopathy may have greater cardiovascular implications, according to a study presented at the American Stroke Association’s (ASA) International Stroke Conference (ISC) 2020 in Los Angeles, US.
The lutein and zeaxanthin status in pregnant women may play a significant role in the visual developmental trajectory of their offspring, such that higher concentrations of these two carotenoids protect against the risk of poor visual acuity (VA) in children, as reported in a study from Singapore.
Unusual involvement of the eyes with atypical presentations may occur in patients with inflammatory bowel diseases (IBD) on antitumour necrosis factor (anti-TNF) therapy, according to a recent study presented at the 2019 Advances in Inflammatory Bowel Diseases Annual Meeting (AIBD 2019).
A recent study reports a mean growth rate of proximal aorta of about 0.1 mm/year in hypertensive patients with known aortic dilatation. In addition, those with increased rather than normal aortic z score have slower dilatation over time.
Knee osteoarthritis (OA), whether symptomatic or radiographic, contributes to an increased risk of all-cause mortality, with the risk increase from symptomatic knee OA partially attributed to its effect on disability and quality of life (QoL).
It takes just less than 4 days for COVID-19 to spread from one person to another and cause symptoms, and more than 10 percent of the cases are infected by a person who has caught the virus but yet to show symptoms, recent studies suggest.