Microvascular abnormalities in the retina (ie, retinopathy*) may signify greater risks of neurologic disorders such as stroke and dementia, with more severe retinopathy conferring a higher mortality risk, according to data presented at ISC 2021.
The ocular hypotensive agent omidenepag isopropyl (OMDI) was noninferior to the current standard of care, latanoprost, in reducing intraocular pressure (IOP) in individuals with ocular hypertension (OHT) or primary open-angle glaucoma, results of the phase III AYAME study have shown.
Heavy caffeine intake appears to contribute to higher intraocular pressure (IOP) and glaucoma prevalence, but only among individuals with the highest genetic susceptibility to elevated IOP, as shown in a study.
While early-phase clinical trials may demonstrate substantial levels of overall response rates in patients with relapsed/refractory multiple myeloma (RRMM), high heterogeneity of evidence prevents the accurate assessment of clinical benefit before patient participation, reports a recent meta-analysis.
The COVID-19 vaccine AZD1222 by AstraZeneca and the University of Oxford was 79 percent effective overall in preventing symptomatic infections – higher than observed in previous clinical trials of the vaccine – at the interim analysis of a US phase III trial.
Migraine and headache are common ailments of people living in the modern era. Dr Jon Marshall of The Singapore Headache and Migraine Clinic shares his insights with Pearl Toh on how to manage migraine and headache using non-pharmaceutical strategies, with a focus on the manual medicine approach.