Asians who use angiotensin-converting enzyme inhibitors, fibrates, alpha-glucosidase inhibitors or insulin are likely to have cortical cataract, independent of the presence of hypertension, hyperlipidaemia or diabetes, according to data from the Singapore Epidemiology of Eye Diseases (SEED) study.
The fixed-dose combination of brinzolamide 1% and brimonidine 0.2% (BBFC) is superior to vehicle in lowering intraocular pressure (IOP) over a 24-hour period following 4 weeks of 3-times-daily treatment in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT), a study has shown.
A novel incentive strategy which rewards patients who are compliant to their medications significantly improves adherence rates, thus providing a potential cost-effective adherence intervention, the SIGMA* study shows.
Presenting and best-corrected bilateral visual impairment (VI) and blindness are uncommon among Singaporeans, according to a new study. Important risk factors include the Malay ethnicity and advanced age and cataracts.
A recent study by investigators from the Chinese University of Hong Kong (CUHK) showed that low-concentration atropine eye drops could reduce myopia progression in school children by up to nearly 70 percent.
Ranibizumab-related improvements in diabetic retinopathy (DR) severity continue in >70 percent of patients in the open-label extension (OLE) of the RIDE and RISE studies after switching from ranibizumab monthly to an individualized ranibizumab 0.5 mg pro re nata (PRN) dosing regimen.
Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.
Implementation of the collaborative care in a rheumatoid arthritis (RA) clinic has led to improvements in nonbiologic disease-modifying antirheumatic drugs (nb-DMARDs) optimization, adherence to safety recommendations on nb-DMARD monitoring and detection of adverse drug events in RA patients, according to a Singapore study.
Use of menopausal hormone therapy (MHT) was associated with a significantly increased risk of invasive breast cancer, which became progressively greater with longer duration of use, a meta-analysis of worldwide prospective epidemiological studies has shown.