Transdermal androgen appears beneficial to ageing patients with sex hormone deficiency-associated dry eye, with a recent study showing that short-term treatment relieves both symptoms and signs of the condition, as well as improves quality of life (QOL). These benefits are achieved without increasing the incidence of serious side effects.
The duration of action and long-term efficacy of dexamethasone implant in patients with persistent diabetic macular oedema (DMO) do not appear to be negatively affected by vitrectomy, a recent study has shown.
Treatment with subthreshold nanosecond laser does not appear to effectively slow down the rate of progression to late age-related macular degeneration in patients with intermediate disease, according to the results of the LEAD trial.
The efficacy of intravenous methylprednisolone for treating moderate-to-severe active thyroid-associated ophthalmopathy may be predicted by factors such as levels of thyroid stimulating hormone (TSH), anti-TSH-receptor antibodies and triglycerides, as well as eye symptom duration, a study reports.
Patients newly diagnosed with glaucoma are highly likely to report depressive symptoms, with risk factors including young age and female sex, among others, a study has found. Depressive symptomatology appears to decrease considerably 1 year after treatment but remains elevated in patients with impaired vision-related quality of life.
Use of oral steroids in acute nonarteritic anterior ischaemic optic neuropathy (NAAION) does not lead to significant improvements in visual acuity at 6 months, but it significantly enhances resolution of disc oedema and allows greater progress in visual evoked response (VER) parameters, reports a recent study.
Treatment with emixustat does not appear to help reduce the growth rate of geographic atrophy in patients with age-related macular degeneration (AMD), according to the results of a phase IIb/III trial.
Adrenal suppression is present in two-thirds of infants tested during treatment with a standard glucocorticoid (GC) protocol after congenital cataract surgery, according to a recent study, noting a significant association between cumulative daily dose of GCs and the test result.
A recent study has shown that ipsilateral infiltration of local anaesthesia (LA) containing epinephrine in the paranasal tissues prior to external dacryocystorhinostomy under total intravenous general anaesthesia (TIVA) results in a 28-percent decrease in mean propofol usage and a 61-percent reduction in remifentanil usage.
The types of bariatric surgery differentially affect the risk of developing acute pancreatitis postoperatively, such that the risk is greater in patients who undergo vertical sleeve gastrectomy vs Roux-en-Y gastric bypass surgery, according to a study. Risk factors include younger age and presence of gallstones.
An adjuvant trastuzumab treatment course shortened to 9 weeks has failed to demonstrate noninferiority to the standard 1-year course in terms of disease-free survival in breast cancer patients, although the shortened course confers benefits for the risk of severe cardiac toxicity, according to the results of the phase III randomized Short-HER study.