Success of Descemet stripping automated endothelial keratoplasty (DSAEK) in the early and entire postoperative period is very probable if without operative complications and when the donor does not have diabetes, a recent study has found.
Age-related macular degeneration is strongly associated with high-density lipoprotein cholesterol and triglycerides, with the magnitude of effect being higher for early disease and related to drusen size and area, a study has found.
Subcutaneous sarilumab shows therapeutic potential in the management of noninfectious uveitis affecting the posterior segment of the eye, especially eyes with uveitic macular oedema, according to the results of the phase II SATURN trial.
Electroretinogram-assessed localized retinal dysfunction in type 1 diabetes mellitus patients appears to occur even in the absence of clinical signs of diabetic retinopathy (DR), and this incidence is associated with ageing, according to a study.
Higher haemoglobin A1c level and more severe diabetic retinopathy for eyes managed with panretinal photocoagulation (PRP) are associated with less vision improvement and an increased risk of developing vision impairing central-involved diabetic macular oedema (DME), a study has shown.
Transdermal androgen appears beneficial to ageing patients with sex hormone deficiency-associated dry eye, with a recent study showing that short-term treatment relieves both symptoms and signs of the condition, as well as improves quality of life (QOL). These benefits are achieved without increasing the incidence of serious side effects.
The duration of action and long-term efficacy of dexamethasone implant in patients with persistent diabetic macular oedema (DMO) do not appear to be negatively affected by vitrectomy, a recent study has shown.
A strong belief in the necessity of medication is associated with better adherence to oral disease-modifying antirheumatic drugs (DMARDs) or prednisone, while higher self-efficacy correlates with poor adherence, in a diverse cohort of patients with rheumatoid arthritis (RA), suggests a study.
First-line therapy with the BTK* inhibitor ibrutinib plus the anti-CD20 immunotherapy rituximab confers significant survival advantage over the current gold-standard regimen of fludarabine, cyclophosphamide, and rituximab (FCR) for young, fit patients with treatment-naïve chronic lymphocytic leukaemia (CLL), according to the E1912 trial, a large cooperative group study supported by the US National Cancer Institute.
Percutaneous coronary intervention (PCI) displays comparable rates of mortality and serious composite outcomes but a higher rate of target-vessel revascularization at 10 years relative to coronary artery bypass grafting (CABG) in patients with significant left main coronary artery (LMCA) disease, reports a study. On the other hand, CABG delivers lower mortality and serious composite outcome rates compared with PCI with drug-eluting stents after 5 years.