In paediatric patients with microbial keratitis, the most significant risk factors are contact lens wear, trauma, and existing ocular disease, while pre-existing corneal disease and delay in presentation correlate with poor visual acuity, according to a study.
Intravitreal injection (IVI) of brolucizumab for the treatment of neovascular age-related macular degeneration results in variable occlusion of large or small retinal arteries, or both, and perivenular abnormalities, which characterize retinal vasculitis and intraocular inflammation (IOI), a study has found.
Treatment with antivascular endothelial growth factor (anti-VEGF), along with regular monitoring, minimizes the risk of long-term vision loss in patients with neovascular age-related macular degeneration (AMD), a recent study has shown.
Selective laser trabeculoplasty appears to be more favourable than medical therapy in the first-line treatment of patients with ocular hypertension and glaucoma, with the former associated with slower visual field (VF) progression, according to data from the Laser in Glaucoma and Ocular Hypertension Trial (LiGHT).
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Extremes of sleep duration (≤5 or ≥10 hours/day), which is a known mortality risk factor in the general population, may increase absolute mortality in adults with type 2 diabetes (T2D), a prospective study has shown.
Insulin icodec, an in-development basal insulin analogue administered once weekly, was as effective as once-daily insulin glargine in patients with type 2 diabetes (T2D) insufficiently controlled with metformin with or without a DPP-4* inhibitor, according to a phase II trial presented at EASD 2020.