There appears to be an association between obstructive sleep apnoea (OSA) and preclinical thinning of the peripapillary retinal nerve fibre layer (RNFL) in young adults, according to a study. This suggests that individuals with OSA since young adulthood may be at increased risk of glaucoma.
Implantation of intraocular lens (IOL) during early childhood leads to a higher incidence of visual axis opacities compared with aphakia, making it not suitable for children aged ≤6 months, reports a study.
Individuals with glaucoma are more likely to experience increased night-time blood pressure (BP) independent of known risk factors such as age, obesity and diabetes as compared with those who do not have the eye disease, a study reports.
Use of Rose Bengal photodynamic antimicrobial therapy in the adjunct setting shows promise in the management of severe, progressive infectious keratitis prior to a therapeutic keratoplasty, according to the results of a pilot trial.
Acute cerebral ischaemia is detected by magnetic resonance imaging (MRI) in 30 percent of patients with acute central retinal artery occlusion (CRAO) and 25 percent of those with acute branch retinal artery occlusion (BRAO), results of a systematic review and meta-analysis have shown.
A large case series of enucleations has shown a low rate of implant exposure, which indicates that absence of wrapping material around hydroxyapatite orbital implants does not compromise surgical outcomes. It has also reduced surgical time and prevented complications from wrapping materials.
Low-risk histopathologic features at primary enucleation are predicted by the presence of macular sparing, optic nerve visibility, <1 quadrant of retinal detachment (RD) or a combination thereof, which suggest safe trial eye salvage, according to a study. No clinical sign is associated with high-risk histopathologic features.
Dual inhibition of angiopoietin (Ang)-2 and vascular endothelial growth factor (VEGF)-A with faricimab induces meaningful and superior visual acuity improvements compared with ranibizumab in patients with diabetic macular oedema, according to the results of the phase II BOULEVARD trial.
Administering intranasal desmopressin to patients with renal dysfunction not requiring haemodialysis reduces bleeding complications during renal biopsies, especially minor complications such as perinephric haematomas, a study has found. However, it may increase the risk of incident hyponatraemia.
Adding a LAMA* to the double combination therapy of ICS** plus LABA*** in a single inhaler improves lung function and reduces exacerbations in patients whose asthma is inadequately controlled with the combination treatment, according to the TRIMARAN and TRIGGER# studies presented at ERS 2019.